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mir-15 family (RF00455)

Summary
This family represents the related mir-15a and mir-15b sequences. In humans miR-15a and miR-16 are clustered within 0.5 kb at 13q14. This region has been shown to be deleted in more than half of B cell chronic lymphocytic leukaemias (CLL). Both miR-15a and miR-16 are deleted or down-regulated in more than two thirds of CLL cases [2]. The mature sequence is excised from the 5' arm of the hairpin. The family represents the microRNA (miRNA) precursor mir-125 imported from miRBase [3].

There are 165 hairpins in the mir-15 family

Name Accession RPM Chromosome Start End Strand Confidence
hsa-mir-15a MI0000069 3371 chr13 50049119 50049201 - High
hsa-mir-16-1 MI0000070 10398 chr13 50048973 50049061 - High
hsa-mir-16-2 MI0000115 10575 chr3 160404745 160404825 + High
mmu-mir-15b MI0000140 1511 3 68917105 68917168 + High
mmu-mir-195a MI0000237 1067 11 70125868 70125961 + High
hsa-mir-15b MI0000438 5285 chr3 160404588 160404685 + High
hsa-mir-195 MI0000489 1198 chr17 7017615 7017701 - High
mmu-mir-15a MI0000564 1860 14 61869476 61869559 - High
mmu-mir-16-1 MI0000565 6343 14 61869329 61869421 - High
mmu-mir-16-2 MI0000566 6356 3 68917235 68917329 + High
rno-mir-15b MI0000843 86 chr2 165605923 165606020 + High
rno-mir-16-1 MI0000844 5307 chr2 165606072 165606166 + High
rno-mir-195 MI0000939 1360 chr10 56845301 56845387 + High
gga-mir-16-1 MI0001185 392 1 169278262 169278345 - High
gga-mir-15a MI0001186 73 1 169278404 169278486 - High
gga-mir-16-2 MI0001222 387 9 21896945 21897038 - High
gga-mir-15b MI0001223 27 9 21897120 21897210 - High
dre-mir-15a-1 MI0001891 226 chr1 46722622 46722705 - High
dre-mir-15a-2 MI0001892 178 chr9 29652511 29652612 - High
dre-mir-15b MI0001893 811 chr7 26070874 26071007 + High
dre-mir-16a MI0001894 111 chr15 1543857 1543943 + High
dre-mir-16b MI0001895 740 chr1 46722379 46722518 - High
dre-mir-16c MI0001896 968 chr9 29652352 29652487 - High
dre-mir-457a MI0002177 745 chr7 26071426 26071508 + High
dre-mir-457b MI0002178 144 chr14 31521930 31522007 - High
ssc-mir-15b MI0002419 66 chr13 108388133 108388230 + High
ggo-mir-15b MI0002491 - chr3 162984222 162984319 + High
age-mir-15b MI0002492 - None None -
ppa-mir-15b MI0002493 - chr3 165474898 165474995 + -
ppy-mir-15b MI0002494 - chr3 163674098 163674195 + -
ptr-mir-15b MI0002495 - chr3 164010544 164010641 + High
mml-mir-15b MI0002496 81 2 62678298 62678395 + High
lla-mir-15b MI0002497 - None None -
mne-mir-15b MI0002498 - None None -
ggo-mir-195 MI0002617 - chr17 7023321 7023407 - -
ppa-mir-195 MI0002618 - chr17 7036725 7036811 - -
age-mir-15a MI0002945 - None None -
age-mir-16 MI0002946 - None None -
ggo-mir-15a MI0002947 - chr13 31956667 31956749 - -
ggo-mir-16 MI0002948 - chr13 31956521 31956609 - -
mne-mir-15a MI0002949 - None None -
mne-mir-16 MI0002950 - None None -
sla-mir-15a MI0002951 - None None -
sla-mir-16 MI0002952 - None None -
ppa-mir-15a MI0002953 - chr13 49936235 49936317 - -
ppa-mir-16 MI0002954 - chr13 49936089 49936177 - -
lca-mir-15a MI0002955 - None None -
lca-mir-16 MI0002956 - None None -
mml-mir-15a MI0002957 170 17 28503483 28503565 - High
mml-mir-16-1 MI0002958 643 17 28503337 28503425 - High
ppy-mir-15a MI0002959 - chr13 50305217 50305299 - -
ppy-mir-16-1 MI0002960 - chr13 50305071 50305159 - -
ptr-mir-15a MI0002961 - chr13 35079678 35079760 - High
ptr-mir-16-1 MI0002962 - chr13 35079532 35079620 - High
lla-mir-15a MI0002963 - None None -
lla-mir-16 MI0002964 - None None -
fru-mir-15b MI0003447 - ref|NC_042295.1| 9497432 9497526 + -
tni-mir-15b MI0003448 - 16 2089810 2089900 - High
fru-mir-15a MI0003469 - ref|NC_042285.1| 16522331 16522401 + High
tni-mir-15a MI0003470 - 2 11019282 11019352 + High
fru-mir-16 MI0003471 - ref|NC_042285.1| 16522485 16522573 + High
tni-mir-16a MI0003472 - 2 11019481 11019552 + Medium
bta-mir-16b MI0004739 1506 1 107073622 107073714 - High
dre-mir-15c MI0004779 680 chr15 1543686 1543768 + High
xtr-mir-15a MI0004799 - 2 149439756 149439838 - High
xtr-mir-15b MI0004800 - 5 114788604 114788691 - High
xtr-mir-16c MI0004801 - 8 68469663 68469732 - High
xtr-mir-16a MI0004802 - 2 149439621 149439702 - High
xtr-mir-15c MI0004892 - 8 68471660 68471733 - High
xtr-mir-16b MI0004910 - 5 114788447 114788530 - -
bta-mir-15b MI0005012 173 1 107073765 107073862 - High
mdo-mir-15a MI0005333 59 ref|NC_077230.1| 319027958 319028040 + High
mdo-mir-16-1 MI0005334 364 ref|NC_077230.1| 319028102 319028191 + High
bta-mir-15a MI0005458 355 12 19501061 19501143 - High
bta-mir-195 MI0005459 269 19 26807507 26807593 - High
oan-mir-15c MI0006691 101 6 24804152 24804267 - High
oan-mir-16c MI0006692 6198 6 24803818 24803937 - -
oan-mir-15b MI0006818 28 1 155378966 155379095 + High
oan-mir-16b MI0006819 121 1 155379131 155379231 + High
oan-mir-15a MI0006886 25 20 8171552 8171649 + -
oan-mir-16a MI0006887 404 20 8171681 8171812 + High
gga-mir-15c MI0007562 37 4 4001176 4001251 - High
gga-mir-16c MI0007563 2035 4 4000810 4000880 - High
mml-mir-16-2 MI0007589 653 2 62678455 62678535 + High
mml-mir-195 MI0007658 245 16 6775460 6775546 - High
cfa-mir-15a MI0008048 - 22 1834523 1834581 + High
cfa-mir-16-1 MI0008049 - 22 1834663 1834727 + High
cfa-mir-15b MI0008083 - 34 26517327 26517386 + High
cfa-mir-16-2 MI0008084 - 34 26517471 26517535 + High
cfa-mir-195 MI0008105 - 5 32150422 32150482 - High
ssc-mir-15a MI0008211 102 chrUScaf2048 70414 70492 + High
ssc-mir-16-2 MI0008212 274 chrUScaf2048 70557 70635 + High
ssc-mir-16-1 MI0008213 291 chr13 108388290 108388366 + High
xla-mir-15c-1 MI0008378 - chr8L 48901002 48901075 - High
ptr-mir-16-2 MI0008555 - chr3 164010702 164010781 + High
ptr-mir-195 MI0008568 - chr17 7272655 7272740 - -
bta-mir-16a MI0009753 574 12 19500915 19501003 - High
mdo-mir-195 MI0012517 39 ref|NC_077228.1| 259513635 259513706 + -
eca-mir-15b MI0012706 54 19 3408021 3408084 - High
eca-mir-16-1 MI0012707 3536 19 3407863 3407943 - High
eca-mir-195 MI0012774 783 11 50388621 50388714 - High
eca-mir-15a MI0012829 135 17 21041772 21041828 + High
eca-mir-16-2 MI0012830 3537 17 21041912 21041974 + High
ssc-mir-195 MI0013141 131 chr12 54717315 54717394 + High
tgu-mir-15a MI0013772 - chr1 55909891 55909961 + -
tgu-mir-16a MI0013811 - chr1 55910032 55910123 + -
tgu-mir-16c MI0013814 - chr4A 7178185 7178256 + -
tgu-mir-16b MI0013816 - chr9 25555835 25555906 - -
tgu-mir-15b MI0013825 - chr9 25555991 25556061 - -
tgu-mir-15c MI0013850 - chr4A 7177772 7177853 + -
ppy-mir-16-2 MI0014795 - chr3 163674255 163674336 + -
ppy-mir-195 MI0014857 - chr17 7022698 7022784 - -
pma-mir-15a MI0017011 - ref|NC_046123.1| 1714260 1714334 - -
pma-mir-15b MI0017012 - ref|NW_022638143.1| 26040 26123 + -
pma-mir-16a MI0017013 - ref|NC_046089.1| 3364255 3364329 + -
aca-mir-15b MI0018765 - GL343761.1 167247 167327 + High
aca-mir-15a MI0018766 - chr3 13039114 13039198 - High
aca-mir-16a MI0018770 - chr3 13038961 13039052 - High
aca-mir-16b MI0018771 - GL343761.1 168379 168473 + -
aca-mir-457 MI0018873 - None None -
meu-mir-16c MI0019260 - None None -
ola-mir-16 MI0019491 - 13 12901172 12901274 + High
ola-mir-15a MI0019534 - 21 11191711 11191814 + High
cgr-mir-15a MI0020416 782 JH000694.1 802850 802927 + High
cgr-mir-15b MI0020417 583 JH001756.1 252840 252917 + High
cgr-mir-16-1 MI0020418 1256 JH000694.1 802988 803071 + High
cgr-mir-195 MI0020442 118 JH000064.1 2276744 2276823 + High
ccr-mir-15a-1 MI0023333 - None None High
ccr-mir-15a-2 MI0023337 - None None High
ccr-mir-15b MI0023338 - None None High
ccr-mir-16a MI0023339 - None None High
ccr-mir-16b MI0023340 - None None High
ccr-mir-16c MI0023341 - None None High
ccr-mir-457a MI0023402 - None None High
ccr-mir-457b MI0023403 - None None High
mdo-mir-16-2 MI0023875 371 ref|NC_077233.2| 239506951 239507015 - High
ipu-mir-15a-1 MI0024519 - None None -
ipu-mir-15a-2 MI0024520 - None None -
ipu-mir-15b MI0024521 - None None -
ipu-mir-16b MI0024522 - None None -
ipu-mir-457b MI0024713 - None None -
oar-mir-16b MI0025257 58773 chr1 224971191 224971283 - High
hhi-mir-15a MI0025448 - None None -
ssa-mir-15a MI0026522 - None None High
ssa-mir-15b MI0026523 - None None High
ssa-mir-15c-1 MI0026524 - None None High
ssa-mir-15c-2 MI0026525 - None None High
ssa-mir-15d MI0026526 - None None High
ssa-mir-16a-1 MI0026528 - None None -
ssa-mir-16a-2 MI0026529 - None None High
ssa-mir-16b MI0026530 - None None Medium
ssa-mir-16c MI0026531 - None None Medium
rno-mir-15a MI0030352 277 None None High
chi-mir-15a MI0030644 - chr12 18725978 18726072 - High
chi-mir-15b MI0030645 - chr1 109436450 109436547 - High
chi-mir-16a MI0030646 - chr12 18725843 18725931 - Medium
chi-mir-16b MI0030647 - chr1 109436307 109436403 - High
chi-mir-195 MI0030670 - chr19 27447708 27447798 - High
tch-mir-195 MI0031209 - KB320771.1 1661457 1661517 + High
tch-mir-15b MI0031212 - KB362115.1 352368 352427 + High
tch-mir-15a MI0031221 - KB320426.1 869966 870024 - High
oha-mir-15a MI0031366 - AZIM01000178.1 249265 249363 - -
oha-mir-15b MI0031367 - AZIM01002644.1 127834 127914 + -
oha-mir-16a MI0031368 - AZIM01002914.1 113190 113278 + -
oha-mir-16b MI0031369 - AZIM01000178.1 249110 249192 - -



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