Stem-loop hsa-mir-20b

Accession

MI0001519

Symbol

HGNC: MIR20B

Description

Homo sapiens hsa-mir-20b precursor miRNA mir-17

Gene
family

RF00051; mir-17

Literature search

208 open access papers mention hsa-mir-20b
(659 sentences)

Sequence

12866 reads, 36 reads per million, 136 experiments

aguacCAAAGUGCUCAUAGUGCAGGUAGuuuuggcaugacucuACUGUAGUAUGGGCACUUCCAGuacu
(((((..(((((((((((.(((((..((((.......))))...))))).)))))))))))...)))))

Structure

     -CA           G     -GU    uu 
aguac   AAGUGCUCAUA UGCAG   AGuu  g
|||||   ||||||||||| |||||   ||||  g
ucauG   UUCACGGGUAU AUGUC   ucag  c
     ACC           G     Auc    ua 

Annotation confidence High

Genome context

chrX: 134169809-134169877 [-]

Clustered miRNAs

5 other miRNAs are < 10 kb from hsa-mir-20b

Disease association

hsa-mir-20b is associated with one or more human diseases in the Human microRNA Disease Database

Biological pathways

hsa-mir-20b is involved in one or more biological pathways:

(Source: Reactome)

Biological reactions

hsa-mir-20b is involved in one or more regulation/signalling events:

(Source: Reactome)

Mature hsa-miR-20b-5p

• Accession: MIMAT0001413
• Description: Homo sapiens hsa-miR-20b-5p mature miRNA
• Sequence: 6 - CAAAGUGCUCAUAGUGCAGGUAG - 28
• Evidence: experimental ; array-cloned [2], cloned [3-5]

Mature hsa-miR-20b-3p

• Accession: MIMAT0004752
• Description: Homo sapiens hsa-miR-20b-3p mature miRNA
• Sequence: 44 - ACUGUAGUAUGGGCACUUCCAG - 65
• Evidence: experimental ; cloned [4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 17616659
   Patterns of known and novel small RNAs in human cervical cancer
   "Lui WO, Pourmand N, Patterson BK, Fire A"
   "Cancer Res (2007) 67:6031-6043


3. PubMed ID: 15965474
   Identification of hundreds of conserved and nonconserved human microRNAs
   "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
   "Nat Genet (2005) 37:766-770


4. PubMed ID: 16274478
   Identification of clustered microRNAs using an ab initio prediction method
   Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
   BMC Bioinformatics (2005) 6:267


5. PubMed ID: 15944709
   c-Myc-regulated microRNAs modulate E2F1 expression
   "O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT"
   "Nature (2005) 435:839-843