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miRBase |
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Stem-loop sequence hsa-mir-124-1 |
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Accession | MI0000443 (change log) | ||||
Previous IDs | hsa-mir-124a-1 | ||||
Symbol | HGNC:MIR124-1 | ||||
Description | Homo sapiens miR-124-1 stem-loop | ||||
Gene family | MIPF0000021; mir-124 | ||||
Literature search |
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429 open access papers mention hsa-mir-124-1 | ||||
Stem-loop |
a uc cc a ga uaaau 5' ggccuc ucu guguucac gcg ccuugauu g |||||| ||| |||||||| ||| |||||||| u 3' ucgggg aga cguaagug cgc ggaauuaa c g ua ac g ac cauac |
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Deep sequencing |
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Confidence |
Annotation confidence: high
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Comments |
miR-124 was first identified by cloning studies in mouse [1]. Its expression was later verified in human embryonic stem cells [2]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [5]. The 5' end of the miRNA may be offset with respect to previous annotations. |
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Genome context |
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Database links |
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Mature sequence hsa-miR-124-5p |
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Accession | MIMAT0004591 |
Previous IDs | hsa-miR-124* |
Sequence |
14 - cguguucacagcggaccuugau - 35 |
Deep sequencing | 4370 reads, 22 experiments |
Evidence | experimental; cloned [5] |
Predicted targets |
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Mature sequence hsa-miR-124-3p |
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Accession | MIMAT0000422 |
Previous IDs | hsa-miR-124a;hsa-miR-124 |
Sequence |
53 - uaaggcacgcggugaaugccaa - 74 |
Deep sequencing | 393261 reads, 104 experiments |
Evidence | experimental; cloned [2,4-5] |
Database links |
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Predicted targets |
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References |
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1 |
PMID:12007417
"Identification of tissue-specific microRNAs from mouse"
Curr Biol. 12:735-739(2002).
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2 |
PMID:15183728
"Human embryonic stem cells express a unique set of microRNAs"
Dev Biol. 270:488-498(2004).
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3 |
PMID:12554860
"Numerous microRNPs in neuronal cells containing novel microRNAs"
RNA. 9:180-186(2003).
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4 |
PMID:15325244
"Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells"
Biochem Biophys Res Commun. 322:403-410(2004).
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5 |
PMID:17604727
"A mammalian microRNA expression atlas based on small RNA library sequencing"
Cell. 129:1401-1414(2007).
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