Accession
MI0002017
Description
Danio rerio
dre-mir-152 precursor miRNA
Gene family
MIPF0000056;
mir-148
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
Dre-mir-152 is a microRNA that is involved in various biological processes and has been found to be associated with different genes and networks. It is an anticorrelated miRNA with genes from Cluster 3, along with dre-miR-133a-5p, dre-miR-133a-2-5p, dre-miR-148, dre-miR-22a-3p, and dre-miR-22b-3p [PMC7756072]. It is also linked to the G2M checkpoint along with dre-miR-148, dre-mir-152, dre-miR454b, dre-miR301c-.3p, and dre-miR301b-.3p [PMC7756072]. Dre-mir152 is part of a downregulated ceRNA subnetwork that may be involved in the regulation of osteoclast differentiation [PMC9855694]. It acts as a hub node in a downregulated subnetwork along with MSTRG.29519 and MSTRG.19062 [PMC9855694]. Dre-mir152 targets tspan5a during the growth of IBs [PMC9855694]. Dre mir152 plays a central role in ceRNA networks by targeting 26 mRNAs and 5 lncRNAs along with other miRNAs such as dremiR10c5p, dremiR7, and dremir133b5p [PMC9855694]. The lncRNAs MSTRG.29519 and MSTRG.19062 are targeted by dremir152 and may act as molecular sponges to weaken its negative regulation of tspan5a [PMC9855694]. Dre mir152 has one of the highest expression levels among differentially expressed miRNAs in IB_III [PMC7891300].
Literature search
4 open access papers mention dre-mir-152
(5 sentences)
(5 sentences)
Sequence
2276
reads,
264
reads per million, 11 experiments
cuguucaccuggcucaaguucugugauacacucagacuuugaaucagugguagUCAGUGCAUGACAGAACUUUGGcccgg
.......((.((((.(((((((((.((.((((..((((.............)))))))).)).))))))))).)))).))
.......((.((((.(((((((((.((.((((..((((.............)))))))).)).))))))))).)))).))
Structure
cuguuca u c g a ca uugaa
cc ggcu aaguucugu au cacu gacu u
|| |||| ||||||||| || |||| |||| c
gg ccGG UUCAAGACA UA GUGA CUga a
------- c U G C -- uggug
Annotation confidence
High
Do you think this miRNA is real?
Genome context
chr3: 24095957-24096036 [+]
Database links
Mature dre-miR-152
| Accession | MIMAT0001847 |
| Description | Danio rerio dre-miR-152 mature miRNA |
| Sequence | 54 - UCAGUGCAUGACAGAACUUUGG - 75 |
| Evidence | not_experimental |
| Database links |
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| Predicted targets |
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References
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