miRBase entry: hsa-mir-4749

Stem-loop hsa-mir-4749


Accession
MI0017388
Symbol
HGNC: MIR4749
Description
Homo sapiens hsa-mir-4749 precursor miRNA

Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?

MIR4749 is a molecular entity that has been studied in the context of its interaction with human serum albumin (HSA) [PMC8835948]. The research utilized fluorescence spectroscopy to investigate the binding between HSA and MIR4749 [PMC8835948]. The distance between the donor and acceptor (DDA) in the MIR4749-HSA complex was calculated to be within a range of 3.8 to 4.8 nanometers, with an additional 0.1 nm considered for the dye attached to MIR4749's 5′ end [PMC8835948]. Based on these calculations, complexes with a DDA distance within the range of 3.9 to 4.9 nm were selected for further analysis [PMC8835948].


Sequence

128 reads, 15 reads per million, 41 experiments
ccUGCGGGGACAGGCCAGGGCAUCuaggcugugcacagugaCGCCCCUCCUGCCCCCACAG
.(((.((((.((((...((((.((...((((....)))))).))))..)))).)))).)))

Structure
c   C    A    CCA    A  uag    u 
 cUG GGGG CAGG   GGGC UC   gcug g
 ||| |||| ||||   |||| ||   ||||  
 GAC CCCC GUCC   CCCG ag   ugac c
-   A    C    -UC    C  ---    a 


Annotation confidence High
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Genome context
chr19: 49854591-49854651 [+]

Disease association
hsa-mir-4749 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-4749-5p

Accession MIMAT0019885
Description Homo sapiens hsa-miR-4749-5p mature miRNA
Sequence 3 - UGCGGGGACAGGCCAGGGCAUC - 24
Evidence experimental
Illumina [1]
Database links
Predicted targets

Mature hsa-miR-4749-3p

Accession MIMAT0019886
Description Homo sapiens hsa-miR-4749-3p mature miRNA
Sequence 42 - CGCCCCUCCUGCCCCCACAG - 61
Evidence experimental
Illumina [1]

References

  1. PubMed ID: 21199797
    Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene
    "Persson H, Kvist A, Rego N, Staaf J, Vallon-Christersson J, Luts L, Loman N, Jonsson G, Naya H, Hoglund M, Borg A, Rovira C"
    "Cancer Res (2011) 71:78-86