Stem-loop hsa-mir-4520-1

Accession

MI0016886

Symbol

HGNC: MIR4520-1

Description

Homo sapiens hsa-mir-4520-1 precursor miRNA mir-4520

Gene
family

RF04067; mir-4520

Sequence

338 reads, 3 reads per million, 27 experiments

gugugccaCCUGCGUGUUUUCUGUCCAAaucagaaaaggauUUGGACAGAAAACACGCAGGAAgaaggaa
........(((((((((((((((((((((((.......))))))))))))))))))))))).........

Structure

-gugugcca                       ag 
         CCUGCGUGUUUUCUGUCCAAauc  a
         |||||||||||||||||||||||  a
         GGACGCACAAAAGACAGGUUuag  a
aaggaagAA                       ga 

Annotation confidence Not enough data

Genome context

chr17: 6655440-6655509 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-4520-1

Disease association

hsa-mir-4520-1 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-4520-5p

• Accession: MIMAT0019235
• Description: Homo sapiens hsa-miR-4520-5p mature miRNA
• Sequence: 9 - CCUGCGUGUUUUCUGUCCAA - 28
• Evidence: experimental ; Illumina [1]

Mature hsa-miR-4520-3p

• Accession: MIMAT0019057
• Description: Homo sapiens hsa-miR-4520-3p mature miRNA
• Sequence: 42 - UUGGACAGAAAACACGCAGGAA - 63
• Evidence: experimental ; Illumina [1-3]

References

1. PubMed ID: 20733160
   Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs
   "Jima DD, Zhang J, Jacobs C, Richards KL, Dunphy CH, Choi WW, Au WY, Srivastava G, Czader MB, Rizzieri DA, Lagoo AS, Lugar PL, Mann KP, Flowers CR, Bernal-Mizrachi L, Naresh KN, Evens AM, Gordon LI, Luftig M, Friedman DR, Weinberg JB, Thompson MA, Gill JI,"
   "Blood (2010) 116:e118-e127


2. PubMed ID: 21199797
   Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene
   "Persson H, Kvist A, Rego N, Staaf J, Vallon-Christersson J, Luts L, Loman N, Jonsson G, Naya H, Hoglund M, Borg A, Rovira C"
   "Cancer Res (2011) 71:78-86


3. PubMed ID: 21807764
   Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome
   "Joyce CE, Zhou X, Xia J, Ryan C, Thrash B, Menter A, Zhang W, Bowcock AM"
   "Hum Mol Genet (2011) 20:4025-4040