Stem-loop hsa-mir-4421

Accession

MI0016758

Symbol

HGNC: MIR4421

Description

Homo sapiens hsa-mir-4421 precursor miRNA

Literature search

2 open access papers mention hsa-mir-4421
(4 sentences)

Sequence

1136 reads, 9.0 reads per million, 80 experiments

cugggUCUCCUUUCUGCUGAGAGUUgaacacuuguugggacaACCUGUCUGUGGAAAGGAGCUAccuac
.((((((((((((((((.((.(((((..(........)..))).)).)).)))))))))))..))))).

Structure

c     --           U  G  -   aa acu 
 ugggU  CUCCUUUCUGC GA AG UUg  c   u
 |||||  ||||||||||| || || |||  |    
 auccA  GAGGAAAGGUG CU UC Aac  g   g
c     UC           U  G  C   ag guu 

Annotation confidence Medium

Genome context

chr1: 51059837-51059905 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-4421

Disease association

hsa-mir-4421 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-4421-5p

• Accession: MIMAT0050607
• Description: Homo sapiens hsa-miR-4421-5p mature miRNA
• Sequence: 6 - UCUCCUUUCUGCUGAGAGUU - 25
• Evidence: experimental ; Illumina [1]

Mature hsa-miR-4421-3p

• Accession: MIMAT0018934
• Description: Homo sapiens hsa-miR-4421-3p mature miRNA
• Sequence: 43 - ACCUGUCUGUGGAAAGGAGCUA - 64
• Evidence: experimental ; Illumina [1]

References

1. PubMed ID: 20733160
   Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs
   "Jima DD, Zhang J, Jacobs C, Richards KL, Dunphy CH, Choi WW, Au WY, Srivastava G, Czader MB, Rizzieri DA, Lagoo AS, Lugar PL, Mann KP, Flowers CR, Bernal-Mizrachi L, Naresh KN, Evens AM, Gordon LI, Luftig M, Friedman DR, Weinberg JB, Thompson MA, Gill JI,"
   "Blood (2010) 116:e118-e127