Stem-loop hsa-mir-889

Accession

MI0005540

Symbol

HGNC: MIR889

Description

Homo sapiens hsa-mir-889 precursor miRNA mir-889

Gene
family

RF04293; mir-889

Literature search

10 open access papers mention hsa-mir-889
(21 sentences)

Sequence

6882 reads, 80 reads per million, 76 experiments

gugcuuaaagAAUGGCUGUCCGUAGUAUGGUCucuauauuuaugaugaUUAAUAUCGGACAACCAUUGUuuuaguaucc
(((((.(((.(((((.((((((..((.(((((((.........)).)))))))..)))))).))))).))).)))))..

Structure

--     u   g     C      UA  A     -  uau 
  gugcu aaa AAUGG UGUCCG  GU UGGUC uc   a
  ||||| ||| ||||| ||||||  || ||||| ||   u
  uauga uuU UUACC ACAGGC  UA AUUag ag   u
cc     u   G     A      UA  -     u  uau 

Annotation confidence High

Genome context

chr14: 101047901-101047979 [+]

Clustered miRNAs

19 other miRNAs are < 10 kb from hsa-mir-889

Disease association

hsa-mir-889 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-889-3p

• Accession: MIMAT0004921
• Description: Homo sapiens hsa-miR-889-3p mature miRNA
• Sequence: 49 - UUAAUAUCGGACAACCAUUGU - 69
• Evidence: experimental ; cloned [1], Illumina [2]

Mature hsa-miR-889-5p

• Accession: MIMAT0026719
• Description: Homo sapiens hsa-miR-889-5p mature miRNA
• Sequence: 11 - AAUGGCUGUCCGUAGUAUGGUC - 32
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45