Stem-loop hsa-mir-758

Accession

MI0003757

Symbol

HGNC: MIR758

Description

Homo sapiens hsa-mir-758 precursor miRNA mir-379

Gene
family

RF04292; mir-379

Literature search

14 open access papers mention hsa-mir-758
(44 sentences)

Sequence

729 reads, 14 reads per million, 48 experiments

gccuggauacaugaGAUGGUUGACCAGAGAGCACACgcuuuauuugugccgUUUGUGACCUGGUCCACUAACCcucaguaucuaaugc
...(((((((.((((.((((.((((((.(.(((.((((.........).))).)))..))))))).))))...)))))))))))....

Structure

-gcc       a    --A    U      A -A   C   - uuu 
    uggauac ugaG   UGGU GACCAG G  GCA ACg c   a
    ||||||| ||||   |||| |||||| |  ||| ||| |   u
    aucuaug acuc   AUCA CUGGUC C  UGU Ugc g   u
cgua       -    CCA    C      - AG   U   c ugu 

Annotation confidence High

Genome context

chr14: 101026020-101026107 [+]

Clustered miRNAs

12 other miRNAs are < 10 kb from hsa-mir-758

Disease association

hsa-mir-758 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-758-3p

• Accession: MIMAT0003879
• Description: Homo sapiens hsa-miR-758-3p mature miRNA
• Sequence: 52 - UUUGUGACCUGGUCCACUAACC - 73
• Evidence: experimental ; cloned [1-2], SOLiD [3]

Mature hsa-miR-758-5p

• Accession: MIMAT0022929
• Description: Homo sapiens hsa-miR-758-5p mature miRNA
• Sequence: 15 - GAUGGUUGACCAGAGAGCACAC - 36
• Evidence: experimental ; SOLiD [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16954537
   Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
   "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
   "Genome Res (2006) 16:1289-1298


3. PubMed ID: 22282338
   Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs
   "Voellenkle C, Rooij Jv, Guffanti A, Brini E, Fasanaro P, Isaia E, Croft L, David M, Capogrossi MC, Moles A, Felsani A, Martelli F"
   "RNA (2012) 18:472-484