Stem-loop hsa-mir-33b

Accession

MI0003646

Symbol

HGNC: MIR33B

Description

Homo sapiens hsa-mir-33b precursor miRNA

Literature search

121 open access papers mention hsa-mir-33b
(1295 sentences)

Sequence

8963 reads, 70 reads per million, 85 experiments

gcgggcggccccgcgGUGCAUUGCUGUUGCAUUGCacgugugugaggcgggugCAGUGCCUCGGCAGUGCAGCCCggagccggccccuggcaccac
(((((((((.(((.((((((((((((..(((((((((.(((.....))).)))))))))..)))))))))).))))).))).))))...)).....

Structure

-----  ---    -   c   c  -          UU         g   g 
     gc   gggc ggc ccg gG UGCAUUGCUG  GCAUUGCac ugu u
     ||   |||| ||| ||| || ||||||||||  ||||||||| ||| g
     cg   cccg ccg ggC CC ACGUGACGGC  CGUGACgug gcg a
cacca  guc    g   a   -  G          UC         g   g 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr17: 17813836-17813931 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-33b

Biological pathways

hsa-mir-33b is involved in one or more biological pathways:

(Source: Reactome)

Biological reactions

hsa-mir-33b is involved in one or more regulation/signalling events:

(Source: Reactome)

Mature hsa-miR-33b-5p

• Accession: MIMAT0003301
• Description: Homo sapiens hsa-miR-33b-5p mature miRNA
• Sequence: 16 - GUGCAUUGCUGUUGCAUUGC - 35
• Evidence: experimental ; SAGE [1], cloned [2]

Mature hsa-miR-33b-3p

• Accession: MIMAT0004811
• Description: Homo sapiens hsa-miR-33b-3p mature miRNA
• Sequence: 54 - CAGUGCCUCGGCAGUGCAGCCC - 75
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16505370
   The colorectal microRNAome
   "Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE"
   "Proc Natl Acad Sci U S A (2006) 103:3687-3692