miRBase entry: dre-mir-221

Stem-loop dre-mir-221


Accession
MI0001387
Description
Danio rerio dre-mir-221 precursor miRNA mir-221
Gene
family?
RF00651; mir-221

Literature search
10 open access papers mention dre-mir-221
(74 sentences)

Sequence

34072 reads, 1739 reads per million, 11 experiments
gucgugaACCUGGCAUACAAUGUAGAUUUCUGUgugguacuaucuacAGCUACAUUGUCUGCUGGGUUUCaggccagcagaauaauucugcuc
(((..((((((((((.(((((((((....(((((.(((...))))))))))))))))).))))))))))..))).(((((((...))))))).

Structure
-------------------   gu          U         AUUU     u   a 
                   guc  gaACCUGGCA ACAAUGUAG    CUGUg ggu  
                   |||  |||||||||| |||||||||    ||||| ||| c
                   cgg  UUUGGGUCGU UGUUACAUC    GAcau cua  
cucgucuuaauaagacgac   aC          C         ----     -   u 


Annotation confidence High
Do you think this miRNA is real?

Genome context
chr9: 33920932-33921024 [-]
Clustered miRNAs
1 other miRNA is < 10 kb from dre-mir-221
Name Accession Chromosome Start End Strand Confidence




Database links

Mature dre-miR-221-3p

Accession MIMAT0001288
Description Danio rerio dre-miR-221-3p mature miRNA
Sequence 48 - AGCUACAUUGUCUGCUGGGUUUC - 70
Evidence experimental
cloned [1-2]
Database links
Predicted targets

Mature dre-miR-221-5p

Accession MIMAT0031926
Description Danio rerio dre-miR-221-5p mature miRNA
Sequence 8 - ACCUGGCAUACAAUGUAGAUUUCUGU - 33
Evidence not_experimental
Database links

References

  1. PubMed ID: 12624257
    Vertebrate microRNA genes
    "Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP"
    "Science (2003) 299:1540

  2. PubMed ID: 15937218
    The developmental miRNA profiles of zebrafish as determined by small RNA cloning
    "Chen PY, Manninga H, Slanchev K, Chien M, Russo JJ, Ju J, Sheridan R, John B, Marks DS, Gaidatzis D, Sander C, Zavolan M, Tuschl T"
    "Genes Dev (2005) 19:1288-1293