miRBase entry: hsa-mir-365a

Stem-loop hsa-mir-365a


Accession
MI0000767
Symbol
HGNC: MIR365A
Description
Homo sapiens hsa-mir-365a precursor miRNA
Gene family
MIPF0000061; mir-365

Literature search
70 open access papers mention hsa-mir-365a
(353 sentences)

Sequence

81427 reads, 1068 reads per million, 129 experiments
accgcagggaaaaugAGGGACUUUUGGGGGCAGAUGUGuuuccauuccacuaucaUAAUGCCCCUAAAAAUCCUUAUugcucuugca
...((((((..((((((((..(((((((((((((((((.........))).)))....))))))))))).))))))))..)))))).

Structure
acc      aa        AC           ----   -   uuu 
   gcaggg  aaugAGGG  UUUUGGGGGCA    GAU GUG   c
   ||||||  ||||||||  |||||||||||    ||| |||   c
   cguucu  uUAUUCCU  AAAAUCCCCGU    cua cac   a
--a      cg        -A           AAUa   u   cuu 


Annotation confidence High
Do you think this miRNA is real?
Comments
Xie et al. [1] refer to this sequence by the internal identifier MIR245. The sequence is unrelated to C. elegans mir-245 (MIR:MI0000321).

Genome context
chr16: 14309285-14309371 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from hsa-mir-365a
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-365a is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-365a-3p

Accession MIMAT0000710
Description Homo sapiens hsa-miR-365a-3p mature miRNA
Sequence 56 - UAAUGCCCCUAAAAAUCCUUAU - 77
Evidence experimental
cloned [1,3-4], array-cloned [2]
Database links
Predicted targets

Mature hsa-miR-365a-5p

Accession MIMAT0009199
Description Homo sapiens hsa-miR-365a-5p mature miRNA
Sequence 16 - AGGGACUUUUGGGGGCAGAUGUG - 38
Evidence not_experimental
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 17616659
    Patterns of known and novel small RNAs in human cervical cancer
    "Lui WO, Pourmand N, Patterson BK, Fire A"
    "Cancer Res (2007) 67:6031-6043

  3. PubMed ID: 15965474
    Identification of hundreds of conserved and nonconserved human microRNAs
    "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
    "Nat Genet (2005) 37:766-770

  4. PubMed ID: 15735639
    Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals
    "Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M"
    "Nature (2005) 434:338-345