miRBase entry: cel-mir-357

Stem-loop cel-mir-357

Caenorhabditis elegans cel-mir-357 precursor miRNA
Gene family
MIPF0000227; mir-357

Literature search
1 open access papers mention cel-mir-357
(4 sentences)


1221 reads, 20 reads per million, 13 experiments

a   --ug       cacca      C   A     -   C    A     gaaca 
 cgc    uacuacu     gcggau CCU CAACG CUG GCAU UGCau     c
 |||    |||||||     |||||| ||| ||||| ||| |||| |||||     a
 gcg    augauga     cgcuUG GGA GUUGC GAC CGUA Augua     a
c   uaaa       -caua      A   C     U   -    A     aaagu 

Annotation confidence Not enough data
Do you think this miRNA is real?
This miRNA was predicted by computational analysis of C. elegans and C. briggsae, and expression of the mature microRNA confirmed by PCR amplification, cloning and sequencing [1]. The extents of the dominant mature miRNA species are adjusted here in accordance with a large scale cloning and sequencing study [2].

Genome context
chrV: 8580542-8580651 [-]
Clustered miRNAs
1 other miRNA is < 10 kb from cel-mir-357
Name Accession Chromosome Start End Strand Confidence

Database links

Mature cel-miR-357-3p

Accession MIMAT0000699
Description Caenorhabditis elegans cel-miR-357-3p mature miRNA
Evidence experimental
cloned [1-2], PCR [1], Illumina [3,5], CLIPseq [4]
Database links
Predicted targets

Mature cel-miR-357-5p

Accession MIMAT0020343
Description Caenorhabditis elegans cel-miR-357-5p mature miRNA
Evidence experimental
Illumina [5]


  1. PubMed ID: 17174894
    Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
    "Cell (2006) 127:1193-1207

  2. PubMed ID: 19460142
    Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
    Kato M, de Lencastre A, Pincus Z, Slack FJ
    Genome Biol (2009) 10:R54

  3. PubMed ID: 20062054
    Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
    "Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW"
    "Nat Struct Mol Biol (2010) 17:173-179

  4. PubMed ID: 15317971
    Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification
    "Ohler U, Yekta S, Lim LP, Bartel DP, Burge CB"
    "RNA (2004) 10:1309-1322

  5. PubMed ID: 21307183
    Improved annotation of C. elegans microRNAs by deep sequencing reveals structures associated with processing by Drosha and Dicer
    "Warf MB, Johnson WE, Bass BL"
    "RNA (2011) 17:563-577