Stem-loop hsa-mir-206

Accession

MI0000490

Symbol

HGNC: MIR206

Description

Homo sapiens hsa-mir-206 precursor miRNA

Literature search

292 open access papers mention hsa-mir-206
(1929 sentences)

Sequence

22915 reads, 527 reads per million, 57 experiments

ugcuucccgaggccacaugcuucuuuauauccccauauggauuacuuugcuaUGGAAUGUAAGGAAGUGUGUGGuuucggcaagug
.((((.((((((((((((((((((((((((..(((((.(.(......).)))))).)))))))))))))))))))))))).)))).

Structure

u    c                        cc     u g uu 
 gcuu ccgaggccacaugcuucuuuauau  ccaua g a  a
 |||| ||||||||||||||||||||||||  ||||| | |   
 ugaa ggcuuuGGUGUGUGAAGGAAUGUA  GGUau c u  c
g    c                        -A     - g uu 

Annotation confidence Not enough data

Comments

This miRNA sequence is predicted based on homology to a verified miRNA from mouse [1], later verified in human [2].

Genome context

chr6: 52144349-52144434 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-206

Disease association

hsa-mir-206 is associated with one or more human diseases in the Human microRNA Disease Database

Biological pathways

hsa-mir-206 is involved in one or more biological pathways:

(Source: Reactome)

Biological reactions

hsa-mir-206 is involved in one or more regulation/signalling events:

(Source: Reactome)

Mature hsa-miR-206

• Accession: MIMAT0000462
• Description: Homo sapiens hsa-miR-206 mature miRNA
• Sequence: 53 - UGGAAUGUAAGGAAGUGUGUGG - 74
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12554859
   New microRNAs from mouse and human
   "Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T"
   "RNA (2003) 9:175-179