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MIR9-1 is a microRNA that has been studied in the context of lung cancer, and researchers have demonstrated a proapoptotic effect of MIR9-1 in patients with lung cancer [PMC9220270]. Additionally, the suppression of cell proliferation has been attributed to the action of ubiquitin-like with PHD and ring finger domains 1 (UHRF1) [PMC9220270]. The hypermethylation of MIR130B and MIR9-1 genes has been found to be associated with the highest relative risk of death in lung cancer patients [PMC8835734]. These findings suggest that MIR9-1 may play a significant role in the pathogenesis and progression of lung cancer. Further research is needed to fully understand the mechanisms by which MIR9-1 exerts its proapoptotic effect and regulates cell proliferation, as well as its potential as a prognostic marker or therapeutic target in lung cancer.