Stem-loop hsa-mir-30b

Accession

MI0000441

Symbol

HGNC: MIR30B

Description

Homo sapiens hsa-mir-30b precursor miRNA

Literature search

398 open access papers mention hsa-mir-30b
(1810 sentences)

Sequence

147792 reads, 741 reads per million, 136 experiments

accaaguuucaguucaUGUAAACAUCCUACACUCAGCUguaauacauggauuggCUGGGAGGUGGAUGUUUACUUCagcugacuugga
.(((((..((((((...((((((((((.((.((((((((............))))))))..))))))))))))...))))))))))).

Structure

a     uu      caU          U  -A        uaaua 
 ccaag  ucaguu   GUAAACAUCC AC  CUCAGCUg     c
 |||||  ||||||   |||||||||| ||  ||||||||      
 gguuc  agucga   CAUUUGUAGG UG  GGGUCggu     a
a     --      CUU          -  GA        uaggu 

Annotation confidence High

Comments

This miRNA sequence is predicted based on homology to a verified miRNA from mouse [1], later verified in human [2].

Genome context

chr8: 134800520-134800607 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-30b

Mature hsa-miR-30b-5p

• Accession: MIMAT0000420
• Description: Homo sapiens hsa-miR-30b-5p mature miRNA
• Sequence: 17 - UGUAAACAUCCUACACUCAGCU - 38
• Evidence: experimental ; cloned [2-3]

Mature hsa-miR-30b-3p

• Accession: MIMAT0004589
• Description: Homo sapiens hsa-miR-30b-3p mature miRNA
• Sequence: 55 - CUGGGAGGUGGAUGUUUACUUC - 76
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 17616659
   Patterns of known and novel small RNAs in human cervical cancer
   "Lui WO, Pourmand N, Patterson BK, Fire A"
   "Cancer Res (2007) 67:6031-6043


3. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739