Stem-loop hsa-mir-211

Accession

MI0000287

Symbol

HGNC: MIR211

Description

Homo sapiens hsa-mir-211 precursor miRNA mir-204

Gene
family

RF00646; mir-204

Literature search

96 open access papers mention hsa-mir-211
(799 sentences)

Sequence

47750 reads, 639 reads per million, 51 experiments

ucaccuggccaugugacuugugggcUUCCCUUUGUCAUCCUUCGCCUagggcucugagcaggGCAGGGACAGCAAAGGGGUGCucaguugucacuucccacagcacggag
.....(((....(((((...(((((.(((((((((..(((((.((((...(((...))).)))))))))..))))))))).)))))...)))))...)))..........

Structure

-----ucacc   ccau     uug     U         CA     C    agg   c 
          ugg    gugac   ugggc UCCCUUUGU  UCCUU GCCU   gcu  
          |||    |||||   ||||| |||||||||  ||||| ||||   ||| u
          acc    cacug   acuCG GGGGAAACG  AGGGA CGgg   cga  
gaggcacgac   -cuu     uug     U         AC     -    --a   g 

Annotation confidence High

Comments

This human miRNA was predicted by computational methods using conservation with mouse and Fugu rubripes sequences [1]. Expression of the excised miR has been validated in zebrafish, and the ends mapped by cloning. The sequence maps to human chromosome 15.

Genome context

chr15: 31065032-31065141 [-]

Disease association

hsa-mir-211 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-211-5p

• Accession: MIMAT0000268
• Description: Homo sapiens hsa-miR-211-5p mature miRNA
• Sequence: 26 - UUCCCUUUGUCAUCCUUCGCCU - 47
• Evidence: not_experimental

Mature hsa-miR-211-3p

• Accession: MIMAT0022694
• Description: Homo sapiens hsa-miR-211-3p mature miRNA
• Sequence: 63 - GCAGGGACAGCAAAGGGGUGC - 83
• Evidence: not_experimental

References

1. PubMed ID: 12624257
   Vertebrate microRNA genes
   "Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP"
   "Science (2003) 299:1540