Stem-loop hsa-mir-139

Accession

MI0000261

Symbol

HGNC: MIR139

Description

Homo sapiens hsa-mir-139 precursor miRNA mir-139

Gene
family

RF00703; mir-139

Literature search

116 open access papers mention hsa-mir-139
(670 sentences)

Sequence

70528 reads, 229 reads per million, 132 experiments

guguauUCUACAGUGCACGUGUCUCCAGUguggcucggaggcUGGAGACGCGGCCCUGUUGGAGUaac
...((((((((((.((.((((((((((((.(.......).)))))))))))))).))).)))))))..

Structure

gug       -   U  A            g gg 
   uauUCUA CAG GC CGUGUCUCCAGU u  c
   ||||||| ||| || |||||||||||| |  u
   aUGAGGU GUC CG GCGCAGAGGUcg a  c
-ca       U   C  -            g gg 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr11: 72615063-72615130 [-]

Disease association

hsa-mir-139 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-139-5p

• Accession: MIMAT0000250
• Description: Homo sapiens hsa-miR-139-5p mature miRNA
• Sequence: 7 - UCUACAGUGCACGUGUCUCCAGU - 29
• Evidence: experimental ; cloned [2]

Mature hsa-miR-139-3p

• Accession: MIMAT0004552
• Description: Homo sapiens hsa-miR-139-3p mature miRNA
• Sequence: 43 - UGGAGACGCGGCCCUGUUGGAGU - 65
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739