Accession
MI0000101
Symbol
HGNC:
MIR99A
Description
Homo sapiens
hsa-mir-99a precursor miRNA
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR99A is a microRNA that can regulate NOX4 expression by targeting the 3’-UTR [PMC7407884]. In a study on plasma miRNAs in CAP (community-acquired pneumonia), MIR99A was found to be among the most elevated miRNAs [PMC8358855].
Literature search
196 open access papers mention hsa-mir-99a
(1198 sentences)
(1198 sentences)
Sequence
393619
reads,
1967
reads per million, 159 experiments
cccauuggcauaAACCCGUAGAUCCGAUCUUGUGgugaaguggaccgcaCAAGCUCGCUUCUAUGGGUCUGugucagugug
..((((((((((.(((((((((..(((.((((((.((........)))))))).)))..))))))))).))))))))))..
..((((((((((.(((((((((..(((.((((((.((........)))))))).)))..))))))))).))))))))))..
Structure
cc A UC U g aag cauuggcaua ACCCGUAGA CGA CUUGUG ug u |||||||||| ||||||||| ||| |||||| || gugacuguGU UGGGUAUCU GCU GAACac gc g gu C UC C - cag
Annotation confidence
High
Do you think this miRNA is real?
Comments
This sequence is localised to chromosome 21 and was named mir-99-21 in reference [1].
Genome context
chr21: 16539089-16539169 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from hsa-mir-99a
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Disease association
hsa-mir-99a is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-99a-5p
| Accession | MIMAT0000097 |
| Description | Homo sapiens hsa-miR-99a-5p mature miRNA |
| Sequence | 13 - AACCCGUAGAUCCGAUCUUGUG - 34 |
| Evidence |
experimental
cloned [1-3] |
| Database links |
|
| Predicted targets |
|
Mature hsa-miR-99a-3p
| Accession | MIMAT0004511 |
| Description | Homo sapiens hsa-miR-99a-3p mature miRNA |
| Sequence | 50 - CAAGCUCGCUUCUAUGGGUCUG - 71 |
| Evidence |
experimental
cloned [2] |
| Database links |
|
| Predicted targets |
|
References
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