Accession
MI0000081
Symbol
HGNC:
MIR24-2
Description
Homo sapiens
hsa-mir-24-2 precursor miRNA mir-24
Gene
family?
family?
RF00178;
mir-24
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR24-2 is a microRNA implicated in the process of carcinogenesis, as evidenced by its interaction with the long non-coding RNA HULC, which is known to play a significant role in cancer development [PMC7575754]. In the context of bladder cancer (BLCA), research has demonstrated that there is a notable inverse correlation between the expression of COPZ1 and several microRNAs, including MIR24-2 [PMC10137353]. This suggests that MIR24-2 may be involved in regulatory pathways that influence COPZ1 expression, which could be significant given COPZ1's potential role in cancer biology.
Literature search
343 open access papers mention hsa-mir-24-2
(2148 sentences)
(2148 sentences)
Sequence
805083
reads,
3119
reads per million, 144 experiments
cucugccucccgUGCCUACUGAGCUGAAACACAGuugguuuguguacacUGGCUCAGUUCAGCAGGAACAGgg
(((((..(((.((....(((((((((..((((((.....))))))....)))))))))...)).))).)))))
(((((..(((.((....(((((((((..((((((.....))))))....)))))))))...)).))).)))))
Structure
cc c GCCU --AA u
cucug ucc gU ACUGAGCUG ACACAG u
||||| ||| || ||||||||| |||||| g
ggGAC AGG CG UGACUCGGU uguguu g
-A A -ACU caca u
Annotation confidence
High
Do you think this miRNA is real?
Comments
mir-24-2 was identified independently by two groups. This sequence was named miR-24 precursor-19 in reference [2].
Genome context
chr19: 13836287-13836359 [-]
Clustered miRNAs
2 other miRNAs are < 10 kb from hsa-mir-24-2
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Disease association
hsa-mir-24-2 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Biological pathways
hsa-mir-24-2 is involved in one or more biological pathways:
(Source: Reactome)
(Source: Reactome)
Biological reactions
hsa-mir-24-2 is involved in one or more regulation/signalling events:
(Source: Reactome)
(Source: Reactome)
Database links
Mature hsa-miR-24-3p
| Accession | MIMAT0000080 |
| Description | Homo sapiens hsa-miR-24-3p mature miRNA |
| Sequence | 50 - UGGCUCAGUUCAGCAGGAACAG - 71 |
| Evidence |
experimental
cloned [1,4-7], Northern [1], Illumina [8] |
| Database links |
|
| Predicted targets |
|
Mature hsa-miR-24-2-5p
| Accession | MIMAT0004497 |
| Description | Homo sapiens hsa-miR-24-2-5p mature miRNA |
| Sequence | 13 - UGCCUACUGAGCUGAAACACAG - 34 |
| Evidence |
experimental
cloned [6] |
| Database links |
|
| Predicted targets |
|
References
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