miRBase entry: cel-mir-80

Stem-loop cel-mir-80

Caenorhabditis elegans cel-mir-80 precursor miRNA
Gene family
MIPF0000258; mir-80

Literature search
9 open access papers mention cel-mir-80
(304 sentences)


610322 reads, 13185 reads per million, 16 experiments

---auggacac       cucA         --     U  G      ccgca 
           ucguucg    GCUUUCGAC  AUGAU CU AACaau     a
           |||||||    |||||||||  ||||| || ||||||      
           aguaAGC    CGAAAGUUG  UACUA GA Uuguug     g
cuauagagacu       ----         AU     -  G      uaccc 

Annotation confidence High
Do you think this miRNA is real?
mir-80 is conserved in C.briggsae (MIR:MI0000518) [1]. Reference [3] reports the identification of miR-227, which appears to be expressed from the 5' arm of the same precursor.

Genome context
chrIII: 8865270-8865367 [-]
Clustered miRNAs
2 other miRNAs are < 10 kb from cel-mir-80
Name Accession Chromosome Start End Strand Confidence

Database links

Mature cel-miR-80-5p

Accession MIMAT0000052
Description Caenorhabditis elegans cel-miR-80-5p mature miRNA
Evidence experimental
cloned [3], Illumina [6], CLIPseq [7]
Database links
Predicted targets

Mature cel-miR-80-3p

Accession MIMAT0000053
Description Caenorhabditis elegans cel-miR-80-3p mature miRNA
Evidence experimental
cloned [1-4], Northern [1], 454 [5], Illumina [6], CLIPseq [7]
Database links
Predicted targets


  1. PubMed ID: 11679671
    An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    "Lau NC, Lim LP, Weinstein EG, Bartel DP"
    "Science (2001) 294:858-862

  2. PubMed ID: 12672692
    The microRNAs of Caenorhabditis elegans
    "Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP"
    "Genes Dev (2003) 17:991-1008

  3. PubMed ID: 12747828
    MicroRNAs and other tiny endogenous RNAs in C. elegans
    "Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D"
    "Curr Biol (2003) 13:807-818

  4. PubMed ID: 17174894
    Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
    "Cell (2006) 127:1193-1207

  5. PubMed ID: 19460142
    Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
    Kato M, de Lencastre A, Pincus Z, Slack FJ
    Genome Biol (2009) 10:R54

  6. PubMed ID: 20062054
    Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
    "Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW"
    "Nat Struct Mol Biol (2010) 17:173-179

  7. PubMed ID: 11679672
    An extensive class of small RNAs in Caenorhabditis elegans
    "Lee RC, Ambros V"
    "Science (2001) 294:862-864