miRBase entry: cel-mir-72

Stem-loop cel-mir-72

Caenorhabditis elegans cel-mir-72 precursor miRNA
Gene family
MIPF0000277; mir-72

Literature search
6 open access papers mention cel-mir-72
(12 sentences)


10546110 reads, 52125 reads per million, 16 experiments

      ---      a  uA    A     U   AU      augaucgc 
aggucc   cgucag gc  GGCA GAUGU GGC  AGCUGA        u
||||||   |||||| ||  |||| ||||| |||  ||||||        a
uccagg   guaguc cG  CCGU UUACA CCG  UCGAcu        u
      agu      a  CA    C     -   CU      aucaacaa 

Annotation confidence High
Do you think this miRNA is real?
The expression of C. elegans miR-72 was confirmed by PCR amplification, cloning and sequencing. The predicted hairpin precursor sequence presented here is supported by conservation in C. elegans and C. briggsae (MIR:MI0000751), and differs from that shown in [1] (Uwe Ohler, pers. comm.). The extents of the dominant mature miRNA species are adjusted here in accordance with a large scale cloning and sequencing study [5].

Genome context
chrII: 2452838-2452936 [+]

Database links

Mature cel-miR-72-5p

Accession MIMAT0000044
Description Caenorhabditis elegans cel-miR-72-5p mature miRNA
Evidence experimental
cloned [1-4], 454 [5], Illumina [6,8], CLIPseq [7]
Database links
Predicted targets

Mature cel-miR-72-3p

Accession MIMAT0020318
Description Caenorhabditis elegans cel-miR-72-3p mature miRNA
Evidence experimental
Illumina [8]
Database links


  1. PubMed ID: 11679671
    An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    "Lau NC, Lim LP, Weinstein EG, Bartel DP"
    "Science (2001) 294:858-862

  2. PubMed ID: 12672692
    The microRNAs of Caenorhabditis elegans
    "Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP"
    "Genes Dev (2003) 17:991-1008

  3. PubMed ID: 12747828
    MicroRNAs and other tiny endogenous RNAs in C. elegans
    "Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D"
    "Curr Biol (2003) 13:807-818

  4. PubMed ID: 17174894
    Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
    "Cell (2006) 127:1193-1207

  5. PubMed ID: 19460142
    Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
    Kato M, de Lencastre A, Pincus Z, Slack FJ
    Genome Biol (2009) 10:R54

  6. PubMed ID: 20062054
    Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
    "Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW"
    "Nat Struct Mol Biol (2010) 17:173-179

  7. PubMed ID: 11679672
    An extensive class of small RNAs in Caenorhabditis elegans
    "Lee RC, Ambros V"
    "Science (2001) 294:862-864

  8. PubMed ID: 21307183
    Improved annotation of C. elegans microRNAs by deep sequencing reveals structures associated with processing by Drosha and Dicer
    "Warf MB, Johnson WE, Bass BL"
    "RNA (2011) 17:563-577