2 publications mentioning pte-mir-2g-1

Open access articles that are associated with the species Parasteatoda tepidariorum and mention the gene name mir-2g-1. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1

However, the microRNA that switched in the mir-2 family did not contain completely unique mature sequences and relative arm switching may have been over or underestimated.

The seven copies of mir-2 that are located on six different scaffolds are all found close to the ends of the scaffolds, and may therefore possibly be fragments of larger mir-71/ mir-2 clusters (fig. 3).

In this horseshoe crab we found eight copies of mir-71 located on seven scaffolds, of which six also contain at least one copy of mir-2 (fig. 3).

Parasteatoda tepidariorum contains one cluster containing a single copy of mir-71 and three copies of mir-2, and a second cluster, on a different scaffold, also with one copy of mir-71, but with six copies of mir-2 (fig. 3).

In the S. mimosarum and C. sculpturatus genomes we found one scaffold containing one copy of mir-71 and four copies of mir-2 (fig. 3), and a second scaffold with one copy of mir-71 and three copies of mir-2 (fig. 3).

In the spiders, the scorpion and the horseshoe crab, we consistently found at least two copies of mir-71 and more than two copies of mir-2 (fig. 2).

Fig. 3. —The duplicate mir-71/ mir-2 clusters in chelicerate lineages.

The mir-71/ mir-2 cluster is duplicated in spiders (purple), the scorpion (magenta), and the horseshoe crab (blue).

The mir-71/ mir-2 cluster is an invertebrate-specific microRNA cluster that has expanded in arthropods probably due to tandem duplications of mir-2 (Marco et al. 2010; Marco, Hooks, et al. 2012).

There is another scaffold with one copy of mir-71 and one copy of mir-2 located approximately 6 kb from the end of the scaffold.

The arrangement of L. polyphemus mir-71/ mir-2 genes is much more fragmented (fig. 3).

Therefore the mir-71/ mir-2 and mir-100/ let-7/ mir-125 clusters appear to have been duplicated in spiders and scorpions (Arachnopulmonata) and L. polyphemus but not other chelicerates or mandibulates that we surveyed.

In the acariform and parasitiform lineages, the copy numbers of mir-71 and mir-2 are variable, though usually there is one copy of mir-71 and two copies of mir-2 (fig. 2).

This could perhaps be caused by the many paralogs of the mir-3791 and mir-2 families, which were generally 3’ dominant, though both of these families do show instances of arm switching (fig. 4 and supplementary fig. S6, online).

In A. geniculata there is one complete cluster with one mir-71 and four mir-2 copies, all on one scaffold (fig. 3).

There are also two other copies of mir-2, each on approximately 1 kb scaffolds.

2

Furthermore, nearly all of the tandemly duplicated microRNAs in are microRNAs largely specific to this spider (e. g., mir-3971 paralogs) or clustered in arthropods (e. g., mir-2 from the mir-71/mir-2 cluster) (Additional file 11: Table S6) [44].