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4 publications mentioning eca-mir-30c

Open access articles that are associated with the species Equus caballus and mention the gene name mir-30c. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 14
However, our results suggest that HMB modulates miRNA expression which was previously described in connection with various physiological and pathological conditions and could also be affected by HMB in injured muscle tissue: miR-374b—related to lipid and protein metabolism [54], miR-14—regulator of mitochondria function in C2C12 [55, 56], miR-532-3p—regulates mitochondrial fission in cardiac muscle [57], miR-30c—cellular adipogenesis and cardiac hypertrophy and ischemia [58], miR-450a/c and miR-142—negative regulators of cardiac hypertrophy [59], and miR-542 family—regeneration of various tissues [60]. [score:6]
The following cell proliferation-related genes were identified: jak2 (target of identified miR-101, miR-155), rarg (miR-142-3p, miR-30c), pten (miR-146a, miR-374b, miR-193a), ets1 (miR-221/222), and rarb (miR-146a, miR-146b); cell differentiation-related target genes: jak2 (miR-155), pten (miR-1), klf4 (miR-1, miR-146a, miR-206) and ets1 (miR-221/222). [score:5]
Several potential target genes for identified miRNAs were classified as follow: hypertrophy: tpm3 (miR-1, miR-206), tpm1 (miR-142-5p), sgcd (miR-142-5p), cacnb1 (miR-208b), itgav (miR-142-5p), itga2 (miR-30c, miR-128); muscle regeneration-related processes and pathways: cx43 (miR-206), klf4 (miR-30 c), and vegfc (miR-128, miR-133). [score:3]
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2
[+] score: 10
The miR-30 family has been shown to be down-regulated in mdx4cv mice (mo dels for Duchenne muscular dystrophy), with in vitro analysis indicating that miR-30 miRNAs are decreased following injury and are increased during myoblast differentiation [45]. [score:4]
Two members of the miR-30 family, miR-30b-5p and miR-30e-5p, had decreased expression post-exercise. [score:3]
The largest number of gene targets were identified for the miR-30 family members. [score:3]
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3
[+] score: 4
Down-regulation of miR-130 and miR-30 in canine heart plays an important role in the pathogenesis of chronic atrial fibrillation [12]. [score:4]
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4
[+] score: 1
MiR-30C was computationally predicted to bind the 3′UTR of panda ADRA1D gene and miR-199a-5p to the 3′UTR of panda COMT gene (Figure 3 & Figure S2). [score:1]
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