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3 publications mentioning bta-mir-885

Open access articles that are associated with the species Bos taurus and mention the gene name mir-885. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 18
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-mir-21, hsa-mir-26a-1, hsa-mir-27a, hsa-mir-28, hsa-mir-30a, hsa-mir-96, hsa-mir-98, hsa-mir-99a, hsa-mir-103a-2, hsa-mir-103a-1, hsa-mir-196a-1, hsa-mir-199a-1, hsa-mir-148a, hsa-mir-30d, hsa-mir-34a, hsa-mir-196a-2, hsa-mir-199a-2, hsa-mir-23b, hsa-mir-27b, hsa-mir-125b-1, hsa-mir-143, hsa-mir-145, hsa-mir-152, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-194-1, hsa-mir-194-2, hsa-mir-200a, hsa-mir-99b, hsa-mir-26a-2, hsa-mir-378a, hsa-mir-342, hsa-mir-148b, hsa-mir-338, hsa-mir-335, hsa-mir-196b, hsa-mir-484, hsa-mir-486-1, hsa-mir-1271, hsa-mir-378d-2, bta-mir-26a-2, bta-mir-103-1, bta-mir-148a, bta-mir-21, bta-mir-27a, bta-mir-30d, bta-mir-484, bta-mir-99a, bta-mir-125a, bta-mir-125b-1, bta-mir-145, bta-mir-199a-1, bta-mir-27b, bta-mir-98, bta-mir-148b, bta-mir-200a, bta-mir-30a, bta-let-7a-1, bta-mir-342, bta-mir-23b, bta-let-7a-2, bta-let-7a-3, bta-mir-103-2, bta-mir-125b-2, bta-mir-34a, bta-mir-99b, hsa-mir-885, hsa-mir-103b-1, hsa-mir-103b-2, bta-mir-143, bta-mir-152, bta-mir-16a, bta-mir-194-2, bta-mir-196a-2, bta-mir-196a-1, bta-mir-196b, bta-mir-199a-2, bta-mir-26a-1, bta-mir-28, bta-mir-335, bta-mir-338, bta-mir-378-1, bta-mir-486, bta-mir-96, bta-mir-1271, bta-mir-2299, bta-mir-199c, bta-mir-1388, bta-mir-194-1, bta-mir-378-2, hsa-mir-378b, bta-mir-3431, hsa-mir-378c, hsa-mir-4286, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-378i, bta-mir-4286-1, bta-mir-4286-2, hsa-mir-378j, bta-mir-378b, bta-mir-378c, hsa-mir-486-2, bta-mir-378d, bta-mir-194b, bta-mir-194b-2
Our analysis indicates that, about 3594 genes could be targeted by the eleven up-regulated miRNAs (bta-199a-3p, miR-98, miR-378, miR-21-5p, miR-148b, miR-4286, miR-885, miR-196a, miR-23b-3p, bta-miR-199c and miR-3431) whereas 1163 genes could be targeted by the three down-regulated miRNAs (bta-miR-335, miR-200a and bta-miR-2299-5p) in linseed oil -treated cows. [score:11]
Out of this number, 11 were up-regulated (bta-miR-4286, miR-885, miR-199c, miR-199a-3p, miR-3431, miR-98, miR-196a, miR-378, miR-23b-3p, miR-148b and miR-21-5p) while only 3 were down-regulated (miR-200a, miR-335 and miR-2299-5p) (Table  2). [score:7]
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2
[+] score: 12
Based on this hypothesis, including presumptive declines in the expression of miR-196a, miR-885, PPARG2, SCD1, and ELOVL6 by grazing, the significance of the differences in the t-test results for those targets was analyzed at one side. [score:5]
All other miRNAs tested (miR-15a, miR-23b-3p, miR-27b, miR-30d-5p, miR-92a, miR-140, miR-197, miR-345-5p, miR-451, miR-885, miR-2284x, miR-2295, miR-2412, and miR-2478) were not differently expressed between the groups (P > 0.10), except that miR-103 content tended to be higher in the grain-fed cattle than in the grazing cattle (P = 0.057). [score:3]
Notably, we have demonstrated that miR-196a/b and miR-885 in cattle are expressed exclusively in fast-glycolytic semitendinosus (ST) muscle but not in slow-oxidative masseter muscle [4]. [score:3]
Of those miRNAs, the contents of miR-652, miR-30d, miR-301a, miR-345-5p, miR-374b, miR-425-5p, miR-23b-3p, miR-30b-5p, miR-17-5p, miR-98, miR-28, and miR-874 were lower in the plasma of the grazing cattle than in that of the grain-fed cattle, whereas the contents of miR-10b, miR-2368-3p, miR-885, and miR-2425-3p were higher in the plasma of the grazing cattle. [score:1]
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3
[+] score: 12
For instance, miR-885, miR-29b and miR-29c showed a significantly higher expression at D70, D170 and D290 compared with D1 (p < 0.05) after RNA-sequencing and confirmed by qPCR meanwhile miR-193b and miR-155 showed a significantly lower expression at D70, D170 and D290 compared with D1 (p < 0.05) after RNA-sequencing and confirmed by qPCR (Fig. 8). [score:3]
The corresponding most enriched pathways were axonal guidance signalling (miR-29b), calcium signalling (miR-363), granulocyte adhesion and diapedesis (miR-874), cell cycle: G2/M DNA damage checkpoint regulation (miR-6524), retinol biosynthesis (miR-885) and TGF-β signalling (miR-2285t) (Table S9). [score:2]
MiR-885 was the most up-regulated miRNA when GAL was compared with LAC and when INV was compared with GAL (Table S8). [score:2]
MiR-885 can target RET and FRS2 genes in the glial-derived neurotrophic factor (GDNF) family ligand-receptor interactions pathway or DAPK1, CDK6 and NEK2 genes in pyridoxal 5′-phosphate salvage pathway. [score:2]
This suggests an important role for miR-885 during the entire lactation curve. [score:1]
The top most significantly DE miRNAs (p-value ≤ 1.00E-12) or with a log2 fold change (|L2FC|) ≥ 3 and p-value ≤ 1.00E-5) between lactation stages are shown in Table 3 while 58 dynamically DE miRNAs are shown in Table 4. The most significantly up and down DE miRNAs between LAC and GAL were miR-29b (p-value = 2.99E-31) and miR-363 (p-value = 2.13E-22), between GAL and INV were miR-874 (p-value = 9.37E-14) and miR-6524 (p-value = 1.84E-09) and between INV and LAC were miR-885 (p-value = 1.70E-31) and miR-2285t (p-value = 7.18E-24), respectively (Tables 3 and S8a–c). [score:1]
Notably, several of the significant DE miRNAs (miR-29a, miR-29b, miR-29c, miR-29d-3p, miR-885, miR-490, miR-146b and miR-363) have been reported to play roles in mammogenesis, LAC and GAL 4 32. [score:1]
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