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24 publications mentioning rno-mir-191a

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-191a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 32
Another significantly downregulated candidate is miR-191a that belongs to the miR-191/425 cluster and abnormally expressed during different cancers, diabetes and Alzheimer disease. [score:8]
To be specifically mentioned (fold change >2.5), miR-208, miR-19b, miR-133b and miR-30e were significantly upregulated and miR-99b, miR-100, miR-191a, miR-22 andmiR-181a-1 were significantly downregulated. [score:7]
miR-191a that belongs to the miR-191/425 cluster and abnormally expressed during different cancers, diabetes and Alzheimer disease. [score:5]
miR-191a Egr1, Cd4, Casp4, SOCS4, p53 The exrepssion of miR-191a was downregulated during physiological hypertrophy. [score:4]
miR-99b, miR-100, miR-191a, miR-22 and miR-181a were significantly downregulated during hypertrophy (Fig. 2B). [score:4]
There is no previous report on the expression of miR-191 in cardiac system. [score:3]
No previous report on the role of miR-191a in cardiac system. [score:1]
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2
[+] score: 22
In summary, the data analysis supports the view that the down-regulation of four miRs (miR-133b, miR-143, miR-335-5p, miR-1) appears to orchestrate the development of chronic neuropathic pain in Sural-SNI while the up-regulation of seven miRs (miR-133b, miR-145, miR-193b, miR-143, miR-335-5p, miR-191, miR-1) appear to orchestrate the recovery from post-nerve injury induced pain in Tibial-SNI. [score:8]
By using the rationale from our dual SNI variants we interpret that the decrease in expression of four miRs (miR-133b-3p, miR-145, miR-143, and miR-1) contributes to pain while the increase in expression of two miRs (miR-193b-3p and miR-191-5p) limits the level of pain that develops following a sciatic nerve crush. [score:5]
On the other hand, the translation of these ion channels would be predicted to decrease in the Tibial-SNI primary sensory neurons due to the increase in expression of all seven identified miRs (miR-133b, miR-145, miR-193b, miR-143, miR-335-5p, miR-191, miR-1). [score:5]
In both the microarrays (Figure 3A) and qPCR (Figures 3B,C) seven miRs (miR-133b, miR-145, miR-193b, miR-143, miR-335-5p, miR-191, miR-1) had a significantly higher level of expression in Tibial-SNI than in Sural-SNI. [score:3]
Ct values were <30.60 for miR-133b, <27.78 for miR-145, <27.66 for miR-193b, <30.19 for miR-143, <33.69 for miR-335, <23.42 for miR-191, <37.89 for miR-130a, <36.00 for miR-325, <32.04 for miR-1. Reference miRs were: MammU6-4395470 (Ct values < 19.30), snoRNA135-4380912 (Ct values < 33.98), and U87-4386735 (Ct values < 28.32). [score:1]
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3
[+] score: 22
A 12-week treatment with RDE increased the expression of rno-miR-20b-5p and rno-miR-23b-3p and decreased the expression of rno-miR-191a-5p in alveolar bone (Figure 3a–d), which could result in the down-regulation of Jak1, STAT3, Il6r and up-regulation of Il6. [score:11]
This inhibitory effect of RDE occurred via the regulation of miRNA expression (rno-miR-20b-5p, rno-miR-23b-3p and rno-miR-191a-5p) and lead to a down-regulation of high rate of bone turnover resulted from ovariectomy. [score:9]
Name Primers U6F: 5′-GCTTCGGCAGCACATATACTAAAAT-3′ R: 5′-CGCTTCACGAATTTGCGTGTCAT-3′ rno-miR-500-3pGSP: 5′-GGAAGGCACCTGGGCAAG-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-499-3pGSP: 5′-GGGGAACATCACAGCAAGTC-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-214-3pGSP: 5′-GGGGACAGCAGGCACAGAC-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-20b-5pGSP: 5′-GGGGCAAAGTGCTCATAGTG-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-877GSP: 5′-GGGGAAGTAGAGGAGATGGC-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-451-5pGSP: 5′-GGGGGAAACCGTTACCATTAC-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-3577GSP: 5′-GGGTTCTGTCCCTCTTGGC-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-370-3pGSP: 5′-AGCCTGCTGGGGTGGAA-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-181d-5pGSP: 5′-GGGGCATTCATTGTTGTCG-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-23b-3pGSP: 5′-GGGATCACATTGCCAGGG-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-191a-5pGSP: 5′-GGCAACGGAATCCCAAAAG-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-200c-3pGSP: 5′-GGGGTAATACTGCCGGGTAA-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-328a-3pGSP: 5′-AACTCGCCCTCTCTGCCC-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ nutrients-07-01333-t002_Table 2 Table 2 Primers of mRNA targets. [score:1]
Name Primers U6F: 5′-GCTTCGGCAGCACATATACTAAAAT-3′ R: 5′-CGCTTCACGAATTTGCGTGTCAT-3′ rno-miR-500-3pGSP: 5′-GGAAGGCACCTGGGCAAG-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-499-3pGSP: 5′-GGGGAACATCACAGCAAGTC-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-214-3pGSP: 5′-GGGGACAGCAGGCACAGAC-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-20b-5pGSP: 5′-GGGGCAAAGTGCTCATAGTG-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-877GSP: 5′-GGGGAAGTAGAGGAGATGGC-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-451-5pGSP: 5′-GGGGGAAACCGTTACCATTAC-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-3577GSP: 5′-GGGTTCTGTCCCTCTTGGC-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-370-3pGSP: 5′-AGCCTGCTGGGGTGGAA-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-181d-5pGSP: 5′-GGGGCATTCATTGTTGTCG-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-23b-3pGSP: 5′-GGGATCACATTGCCAGGG-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-191a-5pGSP: 5′-GGCAACGGAATCCCAAAAG-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-200c-3pGSP: 5′-GGGGTAATACTGCCGGGTAA-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ rno-miR-328a-3pGSP: 5′-AACTCGCCCTCTCTGCCC-3′ R: 5′-GTGCGTGTCGTGGAGTCG-3′ nutrients-07-01333-t002_Table 2 Table 2 Primers of mRNA targets. [score:1]
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4
[+] score: 16
Of the 482 miRNAs that were expressed in both sham-operated animals and animals subjected to SAH, we found that 4 miRNAs (miR-30a, miR-143, miR-191*, and miR-223) showed statistically significant changes in expression between the experimental groups (Table  1). [score:5]
To confirm the differential expression of miR-30a, miR-143, miR-191*, and miR-223 in SAH and sham animals as well as the lack of differential expression of miR-145, additional qPCR assays were performed. [score:4]
The differential expression of miR-191* and miR-223 could not be confirmed. [score:3]
The other two miRNAs identified in the miRNA screen, miR-191* and miR-223, showed no significant differences in expression between the sham and the other groups (Figure  2). [score:3]
Fold change over sham for miR-30a (A), miR-143 (B), miR-191* (C), miR-223 (D), and miR-145 (E) at 0 h, 1 h, 6 h, and 24 h post-SAH. [score:1]
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5
[+] score: 14
The unique miRNA expression patterns distinguishing the ASH group from the control group were composed of six downregulated (miR-199a-3p, miR-214, miR-93, miR-146a, miR-191 and let-7b) and six upregulated (miR-129, miR-490, miR-21, miR-503, miR-183 and miR-185) miRNAs. [score:9]
Wiskott-Aldrich syndrome protein family member 1 (Wasf1), which was found to be regulated by miR-17-5p, miR-93, miR-191, miR-451, miR-146a and miR-140, has been shown to be a protective alcohol-responsive gene in the prefrontal cortex of human alcoholics (38). [score:2]
For instance, miR-191 may regulate peptidylarginine deiminase type 2 (PAD-2) and brain-derived neurotrophic factor (BDNF). [score:2]
Among the dysregulated miRNAs, miR-490 exhibited an increment in the ASH and AFL groups, while miR-140, miR-7a, miR-451, miR-93, miR-146a and miR-191 levels exhibited a decline in the ASH and AFL groups compared with the respective controls (Table II). [score:1]
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6
[+] score: 12
Repeated cocaine exposure produced an increase in expression of miR-26b and a decrease in expression of miR-191 in CCA rats (p < 0.05 vs. [score:5]
To confirm findings from miRNA array study, five miRNAs (miR-129, miR-135a, miR-191, miRNA-22 and miR-26b) were chosen to examine their expression in rat hippocampus by quantitative RT-PCR (qRT-PCR). [score:3]
Some miRNAs which have been previously reported to be involved in brain disorders and drug abuse, including miR-133b, miR-134, miR-181c, miR-191, miR-22, miR-26b, miR-382, miR-409-3p and miR-504, were found to be changed in their expression following repeated cocaine exposure and subsequent abstinence from cocaine treatment. [score:3]
Other miRNAs, such as miR-181c, miR-191, miR-22, miR-99b*, and miR-369-5p, are also differentially modulated in rat hippocampus during post-status epilepsy [21, 22]. [score:1]
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7
[+] score: 11
Other miRNAs from this paper: rno-mir-16, rno-mir-103-2, rno-mir-103-1, rno-mir-122, rno-mir-191b
From a theoretical perspective, the group of genes, 5S, miR-16, miR-103, miR-191, miR-Let7a and RNU48, and the group of genes, 18S, B2M, HPRT1 and SDHA, can be used for microRNA and for mRNA expression data normalization in our mo dels of acute hepatotoxicity, respectively, because they showed no expression differences. [score:5]
The Pearson correlation coefficient of each gene gave the highest stability expression to miR-16 and miR-191 for microRNA studies and SDHA and 18S for mRNA studies (Data S2). [score:3]
Four microRNAs (miR-16, miR-103, miR-191 and miR-Let7a) and three small RNA genes (5S, U6 and RNU48) were selected as candidate RGs for the normalization of the microRNA RT-qPCR data. [score:1]
5S 20 [30]miR-16 [31] 21miR-103 [31] 21 miR-191 [31] 21 miR-Let7a [31] 21 RNU48 [31] 21 U6 22 [32] 18S ACTB 23 [33] ALB 24 [34] B2M 25 [35] CYCA 26 [36] GAPDH HPRT1 27 [26] SDHA 27 [26] RNA was purified from liver samples of control rats and rats treated with the different hepatotoxins. [score:1]
5S 20 [30]miR-16 [31] 21miR-103 [31] 21 miR-191 [31] 21 miR-Let7a [31] 21 RNU48 [31] 21 U6 22 [32] 18S ACTB 23 [33] ALB 24 [34] B2M 25 [35] CYCA 26 [36] GAPDH HPRT1 27 [26] SDHA 27 [26] RNA was purified from liver samples of control rats and rats treated with the different hepatotoxins. [score:1]
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8
[+] score: 7
In contrast, rno-miR-330-5p, rno-miR-223-5p and rno-miR-191a-3p exhibited the greatest down-regulations, which were approximately four-fold changes. [score:4]
To confirm the deep sequencing results, we used qRT-PCR to assess the expressions of 10 of the miRNAs (miR-183-5p, miR-9a-5p, miR-199a-5p, miR-351-5p, miR200b-3p, miR-191a-3p, miR-181c-3p, miR-330-5p, miR-126a-5p and miR-351-3p) in the 12-pair plasma samples from the hyperoxia rats and controls. [score:3]
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9
[+] score: 7
Relative miRNA expression was quantified by determining the point at which the fluorescence accumulation entered the exponential phase (Ct), and the Ct ratio of the target was normalized to small nuclear RNA U6B (RNU6B) or miR-191. [score:5]
For the six colon tumors shown, data bars indicate mean ± SD, n = 3. An inverse relationship between miR-206 and KLF4 in human primary colon cancersBased on a prior report [25], human primary colon cancers were first screened for a suitable endogenous control (data not shown); miR-191 was selected for subsequent qRT-PCR analyses. [score:1]
For the six colon tumors shown, data bars indicate mean ± SD, n = 3. Based on a prior report [25], human primary colon cancers were first screened for a suitable endogenous control (data not shown); miR-191 was selected for subsequent qRT-PCR analyses. [score:1]
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10
[+] score: 7
The results showed that 14 miRNAs (miR-30a-5p, miR-30e-5p, miR-425-5p, miR-142-3p, miR-191a-3p, miR-215, miR-29b-3p, miR-30b-5p, miR-26a-5p, miR-345-5p, miR-361-5p, miR-185-5p, miR-103-3p) were down-regulated but no miRNA was up-regulated among above three altered miRNAs from microarray in OVX serum by normalizing to miR-25-3p (Fig. 3b). [score:7]
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11
[+] score: 6
The expression of miR-486-5p by RT-qPCR was found to be 9.5 fold higher than that of miR-191-5p in rats. [score:3]
The relative expression of each miRNA to a reference miR-191-5p was calculated by the formula: 2 [−∆CT] (∆C [T=]C [T] (target-reference). [score:3]
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12
[+] score: 4
Relative miRNA expression was determined using the CT method, where CT values of individual miRNA data were normalized to CT values of miR-191a-5p. [score:3]
miR-191a-5p was used as endogenous control. [score:1]
[1 to 20 of 2 sentences]
13
[+] score: 4
Among the miRNAs they identified, similarities in miRNA changes were observed in miR-20b, miR-191 and miR-197 which were down-regulated. [score:4]
[1 to 20 of 1 sentences]
14
[+] score: 3
Lastly, an ABI-Prism 7500 Sequence Detection System (Applied Biosystems, Waltham, MA, USA) and SYBR PrimeScript miRNA RT-PCR Kit (Takara) were used to detect the expression level of specific miRNAs (miR-344a, miR-294, miR-872-3p, miR-133b-3p, and miR-423-3p) and the loading control, miR-191. [score:3]
[1 to 20 of 1 sentences]
15
[+] score: 2
Other miRNAs from this paper: rno-mir-10b, rno-mir-1, rno-mir-191b, rno-mir-155
miR-1, miR-10b, miR-155, and miR-191 are novel regulators of BDNF. [score:2]
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16
[+] score: 1
Reference miRNAs (rno-miR-27b-3p, rno-miR-21-5p, rno-miR-151-3p, rno-miR-191a-5p, mmu-miR-351-5p, rno-miR-125a-5p, rno-miR-181a-5p) were selected using geNorm [6], and reached stability criteria. [score:1]
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17
[+] score: 1
Other miRNAs from this paper: rno-mir-191b
Other promoter sites indicated by this analysis included: a binding site for Aryl Hydrocarbon Receptor (AHR), a sequence recognized by microRNA miR-191 and one motif that does not match any known transcription factor but is present in the promoters of 78 genes included in MSigDB. [score:1]
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18
[+] score: 1
Samples were normalized to miR-191 as a stable endogenous control. [score:1]
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19
[+] score: 1
Other miRNAs from this paper: rno-mir-503-1, rno-mir-191b, rno-mir-503-2
Data are normalized against miR-191 and are shown as mean ± SEM. [score:1]
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20
[+] score: 1
miR-191 was used as an endogenous miRNA. [score:1]
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21
[+] score: 1
On the other hand, miR-191a-5p and -29a-3p showed significant changes only in rats supplemented with BMFC; while miR-195-3p and -148a-5p were the only miRNAs significantly affected in the combined-supplement group. [score:1]
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22
[+] score: 1
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-16-1, hsa-mir-17, hsa-mir-21, hsa-mir-23a, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-25, hsa-mir-26a-1, hsa-mir-26b, hsa-mir-30a, hsa-mir-31, hsa-mir-96, hsa-mir-99a, hsa-mir-16-2, hsa-mir-30c-2, hsa-mir-30d, hsa-mir-182, hsa-mir-183, hsa-mir-211, hsa-mir-217, hsa-mir-218-1, hsa-mir-218-2, hsa-mir-221, hsa-mir-222, hsa-let-7g, hsa-let-7i, hsa-mir-15b, hsa-mir-23b, hsa-mir-30b, hsa-mir-125b-1, hsa-mir-132, hsa-mir-143, hsa-mir-145, hsa-mir-191, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-126, hsa-mir-184, hsa-mir-190a, hsa-mir-195, rno-mir-322-1, rno-let-7d, rno-mir-335, rno-mir-342, rno-mir-135b, hsa-mir-30c-1, hsa-mir-299, hsa-mir-30e, hsa-mir-26a-2, hsa-mir-379, hsa-mir-382, hsa-mir-342, hsa-mir-135b, hsa-mir-335, rno-let-7a-1, rno-let-7a-2, rno-let-7b, rno-let-7c-1, rno-let-7c-2, rno-let-7e, rno-let-7f-1, rno-let-7f-2, rno-let-7i, rno-mir-15b, rno-mir-16, rno-mir-17-1, rno-mir-21, rno-mir-23a, rno-mir-23b, rno-mir-24-1, rno-mir-24-2, rno-mir-25, rno-mir-26a, rno-mir-26b, rno-mir-30c-1, rno-mir-30e, rno-mir-30b, rno-mir-30d, rno-mir-30a, rno-mir-30c-2, rno-mir-31a, rno-mir-96, rno-mir-99a, rno-mir-125a, rno-mir-125b-1, rno-mir-125b-2, rno-mir-126a, rno-mir-132, rno-mir-143, rno-mir-145, rno-mir-183, rno-mir-184, rno-mir-190a-1, rno-mir-195, rno-mir-211, rno-mir-217, rno-mir-218a-2, rno-mir-218a-1, rno-mir-221, rno-mir-222, rno-mir-299a, hsa-mir-384, hsa-mir-20b, hsa-mir-409, hsa-mir-412, hsa-mir-489, hsa-mir-494, rno-mir-489, rno-mir-412, rno-mir-543, rno-mir-542-1, rno-mir-379, rno-mir-494, rno-mir-382, rno-mir-409a, rno-mir-20b, hsa-mir-542, hsa-mir-770, hsa-mir-190b, hsa-mir-543, rno-mir-466c, rno-mir-17-2, rno-mir-182, rno-mir-190b, rno-mir-384, rno-mir-673, rno-mir-674, rno-mir-770, rno-mir-31b, rno-mir-191b, rno-mir-299b, rno-mir-218b, rno-mir-126b, rno-mir-409b, rno-let-7g, rno-mir-190a-2, rno-mir-322-2, rno-mir-542-2, rno-mir-542-3
These include rno-miR-195, rno-miR-125a-5p, rno-let-7a, rno-miR-16, rno-miR-30b-5p, rno-let-7c, rno-let-7b, rno-miR-125b-5p, rno-miR-221, rno-miR-222, rno-miR-26a, rno-miR-322, rno-miR-23a, rno-miR-191, rno-miR-30 family, rno-miR-21, rno-miR-126, rno-miR-23b, rno-miR-145 and rno-miR-494. [score:1]
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23
[+] score: 1
Levels of miR-191 and miR-378 were elevated in the urine of rats dosed with nephrotoxicants [52, 53]. [score:1]
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24
[+] score: 1
Other miRNAs from this paper: rno-mir-126a, rno-mir-191b, rno-mir-126b
Housekeeping beta-glucuronidase gene was used to normalize the amount of PCR products for mRNA samples, and rno-miR-191 for miRNA-126. [score:1]
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