miRBase entry: hsa-mir-4749

Stem-loop hsa-mir-4749


Accession
MI0017388
Symbol
HGNC: MIR4749
Description
Homo sapiens hsa-mir-4749 precursor miRNA

Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?

MIR4749 is a type of microRNA that was studied in the context of its interaction with human serum albumin (HSA). The researchers selected complexes with a DDA (donor-donor acceptor) distance falling in the 3.9–4.9 nm interval, taking into account the calculated DDA distance in the 3.8–4.8 nm interval and an estimated contribution of 0.1 nm from the dye attached to the 5′ end of MIR4749 [PMC8835948]. The interaction between HSA and MIR4749 was initially investigated using fluorescence spectroscopy [PMC8835948].


Sequence

128 reads, 15 reads per million, 41 experiments
ccUGCGGGGACAGGCCAGGGCAUCuaggcugugcacagugaCGCCCCUCCUGCCCCCACAG
.(((.((((.((((...((((.((...((((....)))))).))))..)))).)))).)))

Structure
c   C    A    CCA    A  uag    u 
 cUG GGGG CAGG   GGGC UC   gcug g
 ||| |||| ||||   |||| ||   ||||  
 GAC CCCC GUCC   CCCG ag   ugac c
-   A    C    -UC    C  ---    a 


Annotation confidence High
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Genome context
chr19: 49854591-49854651 [+]

Disease association
hsa-mir-4749 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-4749-5p

Accession MIMAT0019885
Description Homo sapiens hsa-miR-4749-5p mature miRNA
Sequence 3 - UGCGGGGACAGGCCAGGGCAUC - 24
Evidence experimental
Illumina [1]
Database links
Predicted targets

Mature hsa-miR-4749-3p

Accession MIMAT0019886
Description Homo sapiens hsa-miR-4749-3p mature miRNA
Sequence 42 - CGCCCCUCCUGCCCCCACAG - 61
Evidence experimental
Illumina [1]

References

  1. PubMed ID: 21199797
    Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene
    "Persson H, Kvist A, Rego N, Staaf J, Vallon-Christersson J, Luts L, Loman N, Jonsson G, Naya H, Hoglund M, Borg A, Rovira C"
    "Cancer Res (2011) 71:78-86