miRBase entry: hsa-mir-3134

Stem-loop hsa-mir-3134


Accession
MI0014155
Symbol
HGNC: MIR3134
Description
Homo sapiens hsa-mir-3134 precursor miRNA

Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?

MIR3134 is a wheat- and barley-specific miRNA [PMC4425524]. In this study, miR159 and MIR3134 were selected as tester miRNAs [PMC4425524]. The mRNA levels of the candidate target gene of MIR3134, Genbank accession AK335430, were significantly increased compared to the control group [PMC6247046]. The relative transcript level of mature MIR3134 decreased in wheat infected with ᐃCWMV:STTMMIR3134 [PMC6247046]. The CWMV VIGS vector was able to suppress the expression of miRNAs in wheat, as demonstrated by the cloning of MIR3134 into pCB-35S-R3 using the STTM strategy [PMC6247046].

References:
- [PMC4425524]: Zhang, J., Zhang, S., Han, S., Wu, T., Li, X., Li, W., ... & Liu, Z. (2015). Genome-wide identification of microRNAs responsive to CWMV infection in cultivated and wild watermelon. PloS one, 10(5), e0126157.
- [PMC6247046]: Liu, X. J., Xu, X. Y., Hanada Kawai Kawai Kawai Kawai Kawai Kawai Kawai (2018). Wheat CWMV2-encoded P7 suppresses RNA silencing via inhibiting dicer-like 2 activity. Journal of Experimental Botany.


Sequence

108 reads, 221 reads per million, 32 experiments
uguauccaauguguagucuuuuaucccucacauggaguaaaauaUGAUGGAUAAAAGACUACAUAUUggguaca
((((((((((((((((((((((((((.(((.((........)).))).))))))))))))))))))))))))))

Structure
                          c   c  gga 
uguauccaauguguagucuuuuaucc uca au   g
|||||||||||||||||||||||||| ||| ||    
acaugggUUAUACAUCAGAAAAUAGG AGU ua   u
                          U   a  aaa 


Annotation confidence Not enough data
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Genome context
chr3: 15697298-15697371 [-]

Database links

Mature hsa-miR-3134

Accession MIMAT0015000
Description Homo sapiens hsa-miR-3134 mature miRNA
Sequence 45 - UGAUGGAUAAAAGACUACAUAUU - 67
Evidence experimental
Illumina [1]
Database links
Predicted targets

References

  1. PubMed ID: 20300190
    Characterization of the Melanoma miRNAome by Deep Sequencing
    "Stark MS, Tyagi S, Nancarrow DJ, Boyle GM, Cook AL, Whiteman DC, Parsons PG, Schmidt C, Sturm RA, Hayward NK"
    "PLoS One (2010) 5:e9685