Accession
MI0006390
Symbol
HGNC:
MIR1256
Description
Homo sapiens
hsa-mir-1256 precursor miRNA
Gene family
MIPF0000594;
mir-1256
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR1256 is a microRNA that has been implicated in various types of cancer, including breast cancer, bladder tumors, and prostate cancer [PMC9775590]. In a study validating miRNA expression in ameloblastoma tumors, MIR1256 was found to be inconsistently expressed compared to non-ameloblastoma controls [PMC5354851]. Additionally, MIR1256 was found to bind to circHECTD1 and participate in the Ago2 complex [PMC7216265]. In another study, gains covering MIR1256 were observed in a patient with prostate cancer [PMC9775590]. Interestingly, the alteration of MIR1256 was associated with a hazard ratio of less than 1 [PMC8108987]. Furthermore, miR1299 and miR548X were also found to be overexpressed in ameloblastomas [PMC7920560]. Overall, MIR1256 is a microRNA that has been implicated in various types of cancer and has been found to be inconsistently expressed in ameloblastoma tumors. It also plays a role in circHECTD1 binding and participates in the Ago2 complex. Additionally, gains covering MIR1256 have been observed in prostate cancer patients. The alteration of MIR1256 is associated with a hazard ratio of less than 1. Furthermore, miR1299 and miR548X have also been found to be overexpressed in ameloblastomas.
Literature search
4 open access papers mention hsa-mir-1256
(5 sentences)
(5 sentences)
Sequence
1430
reads,
59
reads per million, 58 experiments
agucagccuguugaagcuuugaagcuuugaugccAGGCAUUGACUUCUCACUAGCUgugaaaguccuagcuaaagagaagucaaugcaugacaucuuguuucaauagauggcuguuuca
(((((..((((((((((...........((((.((.(((((((((((((..((((((.((...)).))))))..))))))))))))).)).))))..)))))))))).)))))......
(((((..((((((((((...........((((.((.(((((((((((((..((((((.((...)).))))))..))))))))))))).)).))))..)))))))))).)))))......
Structure
------ gc uuugaagcuuu c G AC u a
aguca cuguugaagc gaug cA GCAUUGACUUCUC UAGCUg ga
||||| |||||||||| |||| || ||||||||||||| |||||| || a
ucggu gauaacuuug cuac gu cguaacugaagag aucgau cu
acuuug -a ---------uu a a aa c g
Annotation confidence
Not enough data
Do you think this miRNA is real?
Genome context
chr1: 20988314-20988432 [-]
Disease association
hsa-mir-1256 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-1256
| Accession | MIMAT0005907 |
| Description | Homo sapiens hsa-miR-1256 mature miRNA |
| Sequence | 35 - AGGCAUUGACUUCUCACUAGCU - 56 |
| Evidence |
experimental
Illumina [1] |
| Database links |
|
| Predicted targets |
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References
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