Stem-loop hsa-mir-887

Accession

MI0005562

Symbol

HGNC: MIR887

Description

Homo sapiens hsa-mir-887 precursor miRNA

Gene family

MIPF0000554; mir-887

Literature search

12 open access papers mention hsa-mir-887
(21 sentences)

Sequence

5159 reads, 78 reads per million, 105 experiments

gugcagaucCUUGGGAGCCCUGUUAGACUCuggauuuuacacuuggaGUGAACGGGCGCCAUCCCGAGGcuuugcacag
(((((((.((((((((((((((((..(((((((.........))))))).)))))).))..)))))))).)))))))..

Structure

--       u        --  -      AG       auu 
  gugcaga cCUUGGGA  GC CCUGUU  ACUCugg   u
  ||||||| ||||||||  || ||||||  |||||||   u
  cacguuu GGAGCCCU  CG GGGCAA  UGagguu   a
ga       c        AC  C      -G       cac 

Annotation confidence High

Comments

This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques [1]. Expression was later confirmed by cloning [2].

Genome context

chr5: 15935182-15935260 [+]

Disease association

hsa-mir-887 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-887-3p

• Accession: MIMAT0004951
• Description: Homo sapiens hsa-miR-887-3p mature miRNA
• Sequence: 48 - GUGAACGGGCGCCAUCCCGAGG - 69
• Evidence: experimental ; cloned [2], Illumina [3]

Mature hsa-miR-887-5p

• Accession: MIMAT0026720
• Description: Homo sapiens hsa-miR-887-5p mature miRNA
• Sequence: 10 - CUUGGGAGCCCUGUUAGACUC - 30
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16954537
   Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
   "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
   "Genome Res (2006) 16:1289-1298


3. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45