Accession
MI0005543
Symbol
HGNC:
MIR708
Description
Homo sapiens
hsa-mir-708 precursor miRNA
Gene family
MIPF0000397;
mir-708
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR708 is a microRNA that has been studied in various contexts [PMC6961682]. In a study, boxplot diagrams were used to analyze the expression levels of MIR708, and eight outliers were excluded from the data [PMC6961682]. Additionally, transfection of MIR708 mimics resulted in enhanced binding of MIR708 to Ago2, as shown in Figure 4D [PMC10067432]. Another finding from the study was that knockdown of circEZH2E2/E3 increased the binding of MIR708 to Ago2 [PMC10067432]. These results suggest that MIR708 plays a role in binding to Ago2 and may be involved in regulatory processes mediated by circEZH2E2/E3 [PMC10067432]. Further research is needed to fully understand the functional significance of MIR708 and its interactions with other molecules [PMC10067432].
Literature search
67 open access papers mention hsa-mir-708
(464 sentences)
(464 sentences)
Sequence
54168
reads,
475
reads per million, 121 experiments
aacugcccucAAGGAGCUUACAAUCUAGCUGGGgguaaaugacuugcacaugaacaCAACUAGACUGUGAGCUUCUAGagggcaggga
..((((((((.(((((((((((.(((((.((...((..(((.......)))..)).)).))))).))))))))))).))))))))...
..((((((((.(((((((((((.(((((.((...((..(((.......)))..)).)).))))).))))))))))).))))))))...
Structure
-aa A A C GGg aa ac cugcccuc AGGAGCUUACA UCUAG UG gu aug u |||||||| ||||||||||| ||||| || || ||| u gacgggaG UCUUCGAGUGU AGAUC AC ca uac g agg A C A --a ag ac
Annotation confidence
High
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Genome context
chr11: 79402022-79402109 [-]
Disease association
hsa-mir-708 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-708-5p
| Accession | MIMAT0004926 |
| Description | Homo sapiens hsa-miR-708-5p mature miRNA |
| Sequence | 11 - AAGGAGCUUACAAUCUAGCUGGG - 33 |
| Evidence |
experimental
cloned [1-2] |
| Database links |
|
| Predicted targets |
|
Mature hsa-miR-708-3p
| Accession | MIMAT0004927 |
| Description | Homo sapiens hsa-miR-708-3p mature miRNA |
| Sequence | 57 - CAACUAGACUGUGAGCUUCUAG - 78 |
| Evidence |
experimental
cloned [1] |
| Database links |
|
| Predicted targets |
|
References
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