Stem-loop sequence hsa-mir-411

Accession

MI0003675 (change log)

Symbol

HGNC:MIR411

Description

Homo sapiens miR-411 stem-loop

Gene family

MIPF0000126; mir-379

Literature search

33 open access papers mention hsa-mir-411
(135 sentences)

Stem-loop

   --------------       ug   a a    a      a a       - uuu 
5'               ugguacu  gag g uagu gaccgu u gcguacg c   a
                 |||||||  ||| | |||| |||||| | ||||||| |   u
3'               acuauga  cuc c auca cuggca a uguaugc g   c
   gagccccuaccuaa       --   c a    c      c a       a ugu 

Deep sequencing

52615 reads, 86.6 reads per million, 134 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr14: 101023325-101023420 [+]
• Overlapping transcripts:

  antisense

  OTTHUMT00000414334 ; BEGAIN-007; intron 1

  OTTHUMT00000414329 ; BEGAIN-001; intron 2

  OTTHUMT00000414331 ; BEGAIN-005; intron 2

  OTTHUMT00000414332 ; BEGAIN-003; intron 2

  OTTHUMT00000414335 ; BEGAIN-006; intron 2

  OTTHUMT00000414337 ; BEGAIN-004; intron 2

  ENST00000557378 ; BEGAIN-007; intron 1

  ENST00000443071 ; BEGAIN-201; intron 1

  ENST00000355173 ; BEGAIN-001; intron 2

  ENST00000553553 ; BEGAIN-005; intron 2

  ENST00000556188 ; BEGAIN-003; intron 2

  ENST00000554140 ; BEGAIN-006; intron 2

  ENST00000554747 ; BEGAIN-004; intron 2

Clustered miRNAs

< 10kb from hsa-mir-411

• hsa-mir-379: chr14: 101022066-101022132 [+]
• hsa-mir-411: chr14: 101023325-101023420 [+]
• hsa-mir-299: chr14: 101023794-101023856 [+]
• hsa-mir-380: chr14: 101025017-101025077 [+]
• hsa-mir-1197: chr14: 101025564-101025651 [+]
• hsa-mir-323a: chr14: 101025732-101025817 [+]
• hsa-mir-758: chr14: 101026020-101026107 [+]
• hsa-mir-329-1: chr14: 101026785-101026864 [+]
• hsa-mir-329-2: chr14: 101027100-101027183 [+]
• hsa-mir-494: chr14: 101029634-101029714 [+]
• hsa-mir-1193: chr14: 101030052-101030129 [+]
• hsa-mir-543: chr14: 101031987-101032064 [+]

Database links

• EntrezGene:MIR411
• HGNC:MIR411
• RNAcentral:URS0000759C2D_9606
• miRBase Tracker:MI0003675

Mature sequence hsa-miR-411-5p

• Accession: MIMAT0003329
• Previous IDs: hsa-miR-411
• Sequence: 16 - uaguagaccguauagcguacg - 36
• Deep sequencing: 48977 reads, 128 experiments
• Evidence: experimental; Microarray [1], RT-PCR [1], SAGE [1], cloned [2]
• Database links:
  • RNAcentral:URS00000C5BAA_9606
• Predicted targets:
  • TargetMiner:hsa-miR-411-5p
  • TargetScanVert:hsa-miR-411-5p.1
  • miRDB:hsa-miR-411-5p
  • microrna.org:hsa-miR-411-5p

Mature sequence hsa-miR-411-3p

• Accession: MIMAT0004813
• Previous IDs: hsa-miR-411*
• Sequence: 51 - uauguaacacgguccacuaacc - 72
• Deep sequencing: 3634 reads, 120 experiments
• Evidence: experimental; cloned [2]
• Database links:
  • RNAcentral:URS000037DAEA_9606
• Predicted targets:
  • TargetMiner:hsa-miR-411-3p
  • TargetScanVert:hsa-miR-411-3p
  • miRDB:hsa-miR-411-3p
  • microrna.org:hsa-miR-411-3p

References

1. PMID:16505370 "The colorectal microRNAome" Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE Proc Natl Acad Sci U S A. 103:3687-3692(2006).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).