Stem-loop hsa-mir-556

Accession

MI0003562

Symbol

HGNC: MIR556

Description

Homo sapiens hsa-mir-556 precursor miRNA

Gene family

MIPF0000475; mir-556

Literature search

5 open access papers mention hsa-mir-556
(5 sentences)

Sequence

1841 reads, 60 reads per million, 61 experiments

gauaguaauaagaaaGAUGAGCUCAUUGUAAUAUGAGcuucauuuauacauuucAUAUUACCAUUAGCUCAUCUUUuuuauuacuaccuucaaca
..(((((((((((((((((((((.((.((((((((((..............)))))))))).)).))))))))))))))))))))).........

Structure

-------ga                     C  U          cuucau 
         uaguaauaagaaaGAUGAGCU AU GUAAUAUGAG      u
         ||||||||||||||||||||| || ||||||||||       
         aucauuauuuUUUCUACUCGA UA CAUUAUAcuu      u
acaacuucc                     U  C          uacaua 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr1: 162342546-162342640 [+]

Disease association

hsa-mir-556 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-556-5p

• Accession: MIMAT0003220
• Description: Homo sapiens hsa-miR-556-5p mature miRNA
• Sequence: 16 - GAUGAGCUCAUUGUAAUAUGAG - 37
• Evidence: experimental ; SAGE [1], cloned [2]

Mature hsa-miR-556-3p

• Accession: MIMAT0004793
• Description: Homo sapiens hsa-miR-556-3p mature miRNA
• Sequence: 55 - AUAUUACCAUUAGCUCAUCUUU - 76
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16505370
   The colorectal microRNAome
   "Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE"
   "Proc Natl Acad Sci U S A (2006) 103:3687-3692