Stem-loop sequence hsa-mir-502

Accession

MI0003186 (change log)

Symbol

HGNC:MIR502

Description

Homo sapiens miR-502 stem-loop

Gene family

MIPF0000139; mir-500

Literature search

21 open access papers mention hsa-mir-502
(40 sentences)

Stem-loop

   u             -         uau ug     uag   ugg 
5'  gcucccccucucu aauccuugc   c  ggugc   ugc   c
    ||||||||||||| |||||||||   |  |||||   |||   u
3'  cgagggggagaga uuaggaacg   g  ccacg   acg   c
   u             c         --- gu     -ua   uaa 

Deep sequencing

61093 reads, 58.7 reads per million, 155 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

Extensive cloning studies suggest that the 3' product may be the predominant one [2].

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chrX: 50014598-50014683 [+]
• Overlapping transcripts:

  sense

  OTTHUMT00000056562 ; CCNB3-005; intron 1

  OTTHUMT00000056558 ; CCNB3-001; intron 1

  OTTHUMT00000056559 ; CCNB3-002; intron 1

  OTTHUMT00000056560 ; CCNB3-003; intron 1

  OTTHUMT00000056561 ; CCNB3-004; intron 2

  ENST00000491907 ; CCNB3-005; intron 1

  ENST00000376042 ; CCNB3-001; intron 1

  ENST00000376038 ; CCNB3-002; intron 1

  ENST00000476167 ; CCNB3-003; intron 1

  ENST00000493507 ; CCNB3-004; intron 2

Clustered miRNAs

< 10kb from hsa-mir-502

• hsa-mir-500a: chrX: 50008431-50008514 [+]
• hsa-mir-362: chrX: 50008964-50009028 [+]
• hsa-mir-501: chrX: 50009722-50009805 [+]
• hsa-mir-500b: chrX: 50010672-50010750 [+]
• hsa-mir-660: chrX: 50013241-50013337 [+]
• hsa-mir-502: chrX: 50014598-50014683 [+]

Database links

• EntrezGene:MIR502
• HGNC:MIR502
• RNAcentral:URS000075A647_9606
• miRBase Tracker:MI0003186

Mature sequence hsa-miR-502-5p

• Accession: MIMAT0002873
• Previous IDs: hsa-miR-502
• Sequence: 16 - auccuugcuaucugggugcua - 36
• Deep sequencing: 5255 reads, 147 experiments
• Evidence: experimental; array-cloned [1]
• Database links:
  • RNAcentral:URS0000544FF1_9606
• Predicted targets:
  • TargetMiner:hsa-miR-502-5p
  • TargetScanVert:hsa-miR-502-5p
  • miRDB:hsa-miR-502-5p
  • microrna.org:hsa-miR-502-5p

Mature sequence hsa-miR-502-3p

• Accession: MIMAT0004775
• Sequence: 52 - aaugcaccugggcaaggauuca - 73
• Deep sequencing: 55833 reads, 155 experiments
• Evidence: experimental; cloned [2]
• Database links:
  • RNAcentral:URS0000601CC4_9606
• Predicted targets:
  • TargetMiner:hsa-miR-502-3p
  • TargetScanVert:hsa-miR-502-3p
  • miRDB:hsa-miR-502-3p
  • microrna.org:hsa-miR-502-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).