Stem-loop sequence hsa-mir-519a-1

Accession

MI0003178 (change log)

Symbol

HGNC:MIR519A1

Description

Homo sapiens miR-519a-1 stem-loop

Gene family

MIPF0000020; mir-515

Literature search

34 open access papers mention hsa-mir-519a-1
(224 sentences)

Stem-loop

          u                 a         guug  u 
5' cucaggc gugacacucuagaggga gcgcuuucu    uc g
   ||||||| ||||||||||||||||| |||||||||    || a
3' gaguuug cauugugagauuuuccu cgugaaagg    ag a
          u                 a         --aa  a 

Deep sequencing

5621 reads, 11.7 reads per million, 77 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr19: 53752397-53752481 [+]
• Overlapping transcripts:

  antisense

  OTTHUMT00000464189 ; ZNF677-001; intron 3

  OTTHUMT00000464190 ; ZNF677-004; intron 3

  OTTHUMT00000464279 ; ZNF677-007; intron 3

  OTTHUMT00000464191 ; ZNF677-002; intron 3

  OTTHUMT00000464280 ; ZNF677-008; intron 3

  OTTHUMT00000464281 ; ZNF677-006; intron 3

  OTTHUMT00000464282 ; ZNF677-005; intron 3

  OTTHUMT00000464283 ; ZNF677-009; exon 4

  ENST00000598513 ; ZNF677-001; intron 3

  ENST00000594517 ; ZNF677-004; intron 3

  ENST00000599012 ; ZNF677-007; intron 3

  ENST00000594681 ; ZNF677-002; intron 3

  ENST00000598806 ; ZNF677-008; intron 3

  ENST00000601828 ; ZNF677-006; intron 3

  ENST00000601413 ; ZNF677-005; intron 3

  ENST00000333952 ; ZNF677-201; intron 3

  ENST00000595293 ; ZNF677-009; exon 4

Clustered miRNAs

< 10kb from hsa-mir-519a-1

• hsa-mir-520h: chr19: 53742512-53742599 [+]
• hsa-mir-521-1: chr19: 53748636-53748722 [+]
• hsa-mir-522: chr19: 53751211-53751297 [+]
• hsa-mir-519a-1: chr19: 53752397-53752481 [+]
• hsa-mir-527: chr19: 53754018-53754102 [+]
• hsa-mir-516a-1: chr19: 53756741-53756830 [+]
• hsa-mir-1283-2: chr19: 53758232-53758318 [+]
• hsa-mir-516a-2: chr19: 53761133-53761222 [+]
• hsa-mir-519a-2: chr19: 53762344-53762430 [+]

Database links

• EntrezGene:MIR519A1
• HGNC:MIR519A1
• RNAcentral:URS000075A42F_9606
• miRBase Tracker:MI0003178

Mature sequence hsa-miR-519a-5p

• Accession: MIMAT0005452
• Previous IDs: hsa-miR-519a*
• Sequence: 15 - cucuagagggaagcgcuuucug - 36
• Deep sequencing: 1475 reads, 53 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Database links:
  • RNAcentral:URS00005ECFE5_9606
• Predicted targets:
  • TargetMiner:hsa-miR-519a-5p
  • TargetScanVert:hsa-miR-519a-5p
  • miRDB:hsa-miR-519a-5p
  • microrna.org:hsa-miR-519a-5p

Mature sequence hsa-miR-519a-3p

• Accession: MIMAT0002869
• Previous IDs: hsa-miR-519a
• Sequence: 53 - aaagugcauccuuuuagagugu - 74
• Deep sequencing: 8268 reads, 54 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Database links:
  • RNAcentral:URS0000135E29_9606
• Predicted targets:
  • TargetMiner:hsa-miR-519a-3p
  • TargetScanVert:hsa-miR-519a-3p
  • miRDB:hsa-miR-519a-3p
  • microrna.org:hsa-miR-519a-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).