miRBase entry: hsa-mir-526b

Stem-loop hsa-mir-526b


Accession
MI0003150
Symbol
HGNC: MIR526B
Description
Homo sapiens hsa-mir-526b precursor miRNA
Gene family
MIPF0000020; mir-515

Literature search
15 open access papers mention hsa-mir-526b
(46 sentences)

Sequence

52 reads, 27 reads per million, 17 experiments
ucaggcugugaccCUCUUGAGGGAAGCACUUUCUGUugucugaaagaagaGAAAGUGCUUCCUUUUAGAGGCuuacugucuga
((((((.((((.(((((.((((((((((((((((.((.(.....).)).)))))))))))))))).))))).)))).))))))

Structure
      u    c     U                G  g c 
ucaggc guga cCUCU GAGGGAAGCACUUUCU Uu u u
|||||| |||| ||||| |||||||||||||||| || | g
agucug cauu GGAGA UUUCCUUCGUGAAAGa aa a a
      u    C     U                g  g a 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context
chr19: 53694393-53694475 [+]
Clustered miRNAs
10 other miRNAs are < 10 kb from hsa-mir-526b
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-526b is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-526b-5p

Accession MIMAT0002835
Description Homo sapiens hsa-miR-526b-5p mature miRNA
Sequence 14 - CUCUUGAGGGAAGCACUUUCUGU - 36
Evidence experimental
array-cloned [1], cloned [2]

Mature hsa-miR-526b-3p

Accession MIMAT0002836
Description Homo sapiens hsa-miR-526b-3p mature miRNA
Sequence 51 - GAAAGUGCUUCCUUUUAGAGGC - 72
Evidence experimental
array-cloned [1], cloned [2]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 15965474
    Identification of hundreds of conserved and nonconserved human microRNAs
    "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
    "Nat Genet (2005) 37:766-770