Stem-loop sequence hsa-mir-498

Accession

MI0003142 (change log)

Symbol

HGNC:MIR498

Description

Homo sapiens miR-498 stem-loop

Gene family

MIPF0000463; mir-498

Literature search

21 open access papers mention hsa-mir-498
(44 sentences)

Stem-loop

   aaccc        -aag  aag            -        - a     c       uaua 
5'      uccuuggg    ug   cucaggcuguga uuucaagc c ggggg guuuuuc    a
        ||||||||    ||   |||||||||||| |||||||| | ||||| |||||||    c
3'      aggaaucu    ac   gaguuugacacu gaaguucg g ccucc cgaaaag    u
   -uuga        gcua  -ga            c        a a     a       uagg 

Deep sequencing

104 reads, 54.5 reads per million, 44 experiments

Confidence

Annotation confidence: not enough data

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr19: 53674197-53674320 [+]
• Overlapping transcripts:

  antisense

  OTTHUMT00000464179 ; ZNF665-002; intron 1

  OTTHUMT00000464180 ; ZNF665-001; intron 3

  ENST00000600412 ; ZNF665-002; intron 1

  ENST00000396424 ; ZNF665-001; intron 3

Clustered miRNAs

< 10kb from hsa-mir-498

• hsa-mir-512-1: chr19: 53666679-53666762 [+]
• hsa-mir-512-2: chr19: 53669157-53669254 [+]
• hsa-mir-1323: chr19: 53671968-53672040 [+]
• hsa-mir-498: chr19: 53674197-53674320 [+]
• hsa-mir-520e: chr19: 53675711-53675797 [+]
• hsa-mir-515-1: chr19: 53679003-53679085 [+]
• hsa-mir-519e: chr19: 53679940-53680023 [+]
• hsa-mir-520f: chr19: 53682159-53682245 [+]

Database links

• EntrezGene:MIR498
• HGNC:MIR498
• RNAcentral:URS00006C7250_9606
• miRBase Tracker:MI0003142

Mature sequence hsa-miR-498-5p

• Accession: MIMAT0002824
• Sequence: 34 - uuucaagccagggggcguuuuuc - 56
• Deep sequencing: 61 reads, 23 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Database links:
  • RNAcentral:URS00004CCA62_9606
• Predicted targets:
  • TargetScanVert:hsa-miR-498
  • miRDB:hsa-miR-498-5p
  • microrna.org:hsa-miR-498-5p

Mature sequence hsa-miR-498-3p

• Accession: MIMAT0037323
• Sequence: 70 - aaagcaccuccagagcuugaagc - 92
• Deep sequencing: 37 reads, 20 experiments
• Evidence: experimental; Illumina [3]

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:25822230 "Selective microRNA-Offset RNA expression in human embryonic stem cells" Asikainen S, Heikkinen L, Juhila J, Holm F, Weltner J, Trokovic R, Mikkola M, Toivonen S, Balboa D, Lampela R, Icay K, Tuuri T, Otonkoski T, Wong G, Hovatta O PLoS One. 10:e0116668(2015).