Stem-loop hsa-mir-422a

Accession

MI0001444

Symbol

HGNC: MIR422A

Description

Homo sapiens hsa-mir-422a precursor miRNA

Gene family

MIPF0000548; mir-422

Literature search

30 open access papers mention hsa-mir-422a
(247 sentences)

Sequence

11 reads, 0 reads per million, 7 experiments

gagagaagcACUGGACUUAGGGUCAGAAGGCcugagucucucugcugcagaugggcucucugucccugagccaagcuuuguccucccugg
(((.(((((..(((.(((((((.((((.(((((..(((((......).))))))))).)))).)))))))))).)))))...))).....

Structure

-----   --a     AC   A       U    A     ga    - uc 
     gag   gaagc  UGG CUUAGGG CAGA GGCcu  gucu c  u
     |||   |||||  ||| ||||||| |||| |||||  |||| |   
     cuc   uuucg  acc gaguccc gucu ucggg  uaga g  g
ggucc   cug     -a   -       u    c     --    c uc 

Annotation confidence Not enough data

Comments

miR-422a is an predicted paralogue of miR-422b (MIR:MI0001443), later verified in human [2].

Genome context

chr15: 63870930-63871019 [-]

Disease association

hsa-mir-422a is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-422a

• Accession: MIMAT0001339
• Description: Homo sapiens hsa-miR-422a mature miRNA
• Sequence: 10 - ACUGGACUUAGGGUCAGAAGGC - 31
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 15325244
   Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells
   "Kasashima K, Nakamura Y, Kozu T"
   "Biochem Biophys Res Commun (2004) 322:403-410


2. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414