miRBase entry: hsa-mir-301a

Stem-loop hsa-mir-301a


Accession
MI0000745
Symbol
HGNC: MIR301A
Description
Homo sapiens hsa-mir-301a precursor miRNA
Gene family
MIPF0000034; mir-130

Literature search
106 open access papers mention hsa-mir-301a
(566 sentences)

Sequence

71793 reads, 668 reads per million, 133 experiments
acugcuaacgaauGCUCUGACUUUAUUGCACUACUguacuuuacagcuagCAGUGCAAUAGUAUUGUCAAAGCaucugaaagcagg
.(((((..((.(((((.((((.((((((((((.((((........)).)).))))))))))....)))).))))).))..))))).

Structure
a     aa  a     C    ---U          A  -  acu 
 cugcu  cg auGCU UGAC    UUAUUGCACU CU gu   u
 |||||  || ||||| ||||    |||||||||| || ||    
 gacga  gu uaCGA ACUG    GAUAACGUGA ga cg   u
g     aa  c     A    UUAU          C  u  aca 


Annotation confidence High
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Comments
This sequence is the predicted human homologue of mouse miR-301, cloned from mouse embryonic stem cells [1,3]. Its expression has also been confirmed in human ES cells [2].

Genome context
chr17: 59151136-59151221 [-]

Database links

Mature hsa-miR-301a-3p

Accession MIMAT0000688
Description Homo sapiens hsa-miR-301a-3p mature miRNA
Sequence 51 - CAGUGCAAUAGUAUUGUCAAAGC - 73
Evidence experimental
cloned [2,4], Northern [2]
Database links
Predicted targets

Mature hsa-miR-301a-5p

Accession MIMAT0022696
Description Homo sapiens hsa-miR-301a-5p mature miRNA
Sequence 14 - GCUCUGACUUUAUUGCACUACU - 35
Evidence not_experimental
Database links
Predicted targets

References

  1. PubMed ID: 15183728
    Human embryonic stem cells express a unique set of microRNAs
    "Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS, Moon SY, Kim VN, Kim KS"
    "Dev Biol (2004) 270:488-498

  2. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  3. PubMed ID: 12919684
    Embryonic stem cell-specific MicroRNAs
    "Houbaviy HB, Murray MF, Sharp PA"
    "Dev Cell (2003) 5:351-358

  4. PubMed ID: 15634332
    New human and mouse microRNA genes found by homology search
    "Weber MJ"
    "FEBS J (2005) 272:59-73