Stem-loop sequence hsa-mir-30c-1

AccessionMI0000736 (change log)
Symbol HGNC:MIR30C1
DescriptionHomo sapiens miR-30c-1 stem-loop
Gene family MIPF0000005; mir-30
Literature search

384 open access papers mention hsa-mir-30c-1
(1793 sentences)

   a     cu    ugu u       u   aca         ---g  a 
5'  ccaug  guag   g guaaaca ccu   cucucagcu    ug g
    |||||  ||||   | ||||||| |||   |||||||||    ||  
3'  gguac  cguc   c cauuugu ggg   gagggucgg    ac c
   a     --    uuc u       u   --a         ugga  u 
Get sequence
Deep sequencing
1413073 reads, 3.21e+03 reads per million, 159 experiments
Confidence Annotation confidence: high
Feedback: Do you believe this miRNA is real?

miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana et al. [1]. Two human hairpin precursor sequences are predicted based on homology with the mouse sequences, on chromosomes 1 (MI0000736) and 6 (MI0000254) [3]. Expression of miR-30c was later validated in human HL-60 leukemia cells [2].

Genome context
Coordinates (GRCh38; GCA_000001405.15) Overlapping transcripts
chr1: 40757284-40757372 [+]
OTTHUMT00000319380 ; ZMPSTE24-004; intron 1
OTTHUMT00000015766 ; ZMPSTE24-001; intron 9
ENST00000474142 ; ZMPSTE24-004; intron 1
ENST00000372759 ; ZMPSTE24-001; intron 9
Clustered miRNAs
< 10kb from hsa-mir-30c-1
hsa-mir-30echr1: 40754355-40754446 [+]
hsa-mir-30c-1chr1: 40757284-40757372 [+]
Database links

Mature sequence hsa-miR-30c-5p

Accession MIMAT0000244
Previous IDshsa-miR-30c

17 - 


 - 39

Get sequence
Deep sequencing2809908 reads, 159 experiments
Evidence experimental; cloned [2,4-6]
Database links
Predicted targets

Mature sequence hsa-miR-30c-1-3p

Accession MIMAT0004674
Previous IDshsa-miR-30c-1*

56 - 


 - 77

Get sequence
Deep sequencing8434 reads, 156 experiments
Evidence experimental; cloned [5]
Database links
Predicted targets


PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
PMID:15325244 "Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells" Kasashima K, Nakamura Y, Kozu T Biochem Biophys Res Commun. 322:403-410(2004).
PMID:15978578 "Identification of human fetal liver miRNAs by a novel method" Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X FEBS Lett. 579:3849-3854(2005).
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
PMID:17616659 "Patterns of known and novel small RNAs in human cervical cancer" Lui WO, Pourmand N, Patterson BK, Fire A Cancer Res. 67:6031-6043(2007).