Stem-loop sequence mmu-mir-107

Accession

MI0000684 (change log)

Symbol

MGI:Mir107

Description

Mus musculus miR-107 stem-loop

Gene family

MIPF0000024; mir-103

Literature search

89 open access papers mention mmu-mir-107
(440 sentences)

Stem-loop

   -             --c    u  u           c   u   a 
5'  uucucugugcuuu   agcu cu uacaguguugc uug ggc u
    |||||||||||||   |||| || ||||||||||| ||| ||| g
3'  gagagacacgaaa   ucgg ga auguuacgacg aac uug g
   c             cua    -  c           -   -   a 

Deep sequencing

6928750 reads, 1.73e+04 reads per million, 107 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

Mouse mir-107 is predicted [2] based on homology to a cloned miR from human (MI0000114) [1], and later verified in mouse [3,4].

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr19: 34820687-34820773 [-]
• Overlapping transcripts:

  sense

  ENSMUST00000036584 ; Pank1-201; intron 5

  ENSMUST00000112460 ; Pank1-202; intron 5

Database links

• EntrezGene:Mir107
• MGI:Mir107
• RNAcentral:URS000075DC2E_10090
• miRBase Tracker:MI0000684

Mature sequence mmu-miR-107-5p

• Accession: MIMAT0017048
• Previous IDs: mmu-miR-107*
• Sequence: 15 - agcuucuuuacaguguugccuug - 37
• Deep sequencing: 842 reads, 86 experiments
• Evidence: experimental; 454 [6], Illumina [7]
• Database links:
  • RNAcentral:URS0000035FEE_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-107-5p
  • miRDB:mmu-miR-107-5p

Mature sequence mmu-miR-107-3p

• Accession: MIMAT0000647
• Previous IDs: mmu-miR-107
• Sequence: 52 - agcagcauuguacagggcuauca - 74
• Deep sequencing: 6927902 reads, 107 experiments
• Evidence: experimental; cloned [3-4], Illumina [5,7]
• Database links:
  • RNAcentral:URS00005743AE_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-107-3p
  • miRDB:mmu-miR-107-3p
  • microrna.org:mmu-miR-107-3p

References

1. PMID:11914277 "miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs" Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L, Rappsilber J, Mann M, Dreyfuss G Genes Dev. 16:720-728(2002).
2. PMID:15634332 "New human and mouse microRNA genes found by homology search" Weber MJ FEBS J. 272:59-73(2005).
3. PMID:16766679 "Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes" Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H Genes Dev. 20:1732-1743(2006).
4. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
5. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
6. PMID:20668074 "Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68" Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H J Virol. 84:10266-10275(2010).
7. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).