Stem-loop sequence cel-mir-124

Accession

MI0000302 (change log)

Description

Caenorhabditis elegans miR-124 stem-loop

Gene family

MIPF0000021; mir-124

Literature search

12 open access papers mention cel-mir-124
(116 sentences)

Stem-loop

   gu    - -uu     c      g    cua   a       ----    au 
5'   ccca c   gucau uggcau cacc   gug cuuuagu    ggac  c
     |||| |   ||||| |||||| ||||   ||| |||||||    ||||   
3'   gggu g   cggug accgua gugg   cac ggaauca    ucug  u
   --    a uac     c      a    -cg   -       accu    aa 

Deep sequencing

18517 reads, 488 reads per million, 17 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (WBcel235; GCA_000002985.3): chrIV: 11871738-11871833 [+]
• Overlapping transcripts:

  sense

  C29E6.2a ; C29E6.2a; intron 5

  C29E6.2b ; C29E6.2b; intron 5

  antisense

  C29E6.8 ; C29E6.8; exon 1

Database links

• RNAcentral:URS0000324A65_6239
• miRBase Tracker:MI0000302

Mature sequence cel-miR-124-5p

• Accession: MIMAT0015111
• Previous IDs: cel-miR-124*
• Sequence: 18 - gcaugcacccuagugacuuuagu - 40
• Deep sequencing: 2184 reads, 15 experiments
• Evidence: experimental; CLIPseq [5]
• Database links:
  • RNAcentral:URS000016C218_6239
• Predicted targets:
  • microrna.org:cel-miR-124-5p

Mature sequence cel-miR-124-3p

• Accession: MIMAT0000282
• Previous IDs: cel-miR-124
• Sequence: 61 - uaaggcacgcggugaaugcca - 81
• Deep sequencing: 16331 reads, 17 experiments
• Evidence: experimental; cloned [1], Northern [1], 454 [3], Illumina [4], CLIPseq [5]
• Database links:
  • RNAcentral:URS000040D400_6239
• Predicted targets:
  • TargetScanWorm:cel-miR-124
  • microrna.org:cel-miR-124-3p

References

1. PMID:12672692 "The microRNAs of Caenorhabditis elegans" Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP Genes Dev. 17:991-1008(2003).
2. PMID:12747828 "MicroRNAs and other tiny endogenous RNAs in C. elegans" Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D Curr Biol. 13:807-818(2003).
3. PMID:17174894 "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans" Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP Cell. 127:1193-1207(2006).
4. PMID:19460142 "Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development" Kato M, de Lencastre A, Pincus Z, Slack FJ Genome Biol. 10:R54(2009).
5. PMID:20062054 "Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans" Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW Nat Struct Mol Biol. 17:173-179(2010).