miRNA count: 38589 entries

Release 22.1: October 2018

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Latest miRBase blog posts

By sam (June 7, 2018)

MicroRNA Gene Ontology annotations

You might have noticed some additional information on the mature miRNA pages in the last few weeks. See for example: http://mirbase.org/cgi-bin/mature.pl?mature_acc=MIMAT0000123 http://mirbase.org/cgi-bin/mature.pl?mature_acc=MIMAT0000069 The new section “QuickGO function” contains a set of high quality manual annotations of Gene Ontology terms for mature miRNAs, the vast majority of which come from the work of Rachael Huntley et [...]

By sam (March 12, 2018)

miRBase 22 release

After repeated and unreasonable delay, miRBase 22 is finally released. As you might expect with such a long gap, the number of sequences in the database has jumped significantly — by over a third. The vast majority of the increase comes from new microRNA annotations in species not previous represented in the database. Indeed, there [...]

miRBase: the microRNA database

miRBase provides the following services:

To receive email notification of data updates and feature changes please subscribe to the miRBase announcements mailing list. Any queries about the website or naming service should be directed at mirbase@manchester.ac.uk.

miRBase is managed by the Griffiths-Jones lab at the Faculty of Biology, Medicine and Health, University of Manchester with funding from the BBSRC. miRBase was previously hosted and supported by the Wellcome Trust Sanger Institute.

References

If you make use of the data presented here, please cite the following articles in addition to the primary data sources:

miRBase: annotating high confidence microRNAs using deep sequencing data.
Kozomara A, Griffiths-Jones S.
NAR 2014 42:D68-D73

miRBase: integrating microRNA annotation and deep-sequencing data.
Kozomara A, Griffiths-Jones S.
NAR 2011 39:D152-D157

miRBase: tools for microRNA genomics.
Griffiths-Jones S, Saini HK, van Dongen S, Enright AJ.
NAR 2008 36:D154-D158

miRBase: microRNA sequences, targets and gene nomenclature.
Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ.
NAR 2006 34:D140-D144

The microRNA Registry.
Griffiths-Jones S.
NAR 2004 32:D109-D111

The following publications provide guidelines on miRNA annotation:

A uniform system for microRNA annotation.
Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X, Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M, Matzke M, Ruvkun G, Tuschl T.
RNA 2003 9(3):277-279

Criteria for annotation of plant MicroRNAs.
Meyers BC, Axtell MJ, Bartel B, Bartel DP, Baulcombe D, Bowman JL, Cao X, Carrington JC, Chen X, Green PJ, Griffiths-Jones S, Jacobsen SE, Mallory AC, Martienssen RA, Poethig RS, Qi Y, Vaucheret H, Voinnet O, Watanabe Y, Weigel D, Zhu JK.
Plant Cell. 2008 20(12):3186-3190