Accession
MI0031760
Description
Rattus norvegicus
rno-mir-196b-2 precursor miRNA
Literature search
9 open access papers mention rno-mir-196b-2
(40 sentences)
(40 sentences)
Sequence
108647
reads,
123
reads per million, 327 experiments
aacuggucggugauuUAGGUAGUUUCCUGUUGUUGGGauccaccuuucucUCGACAGCACGACACUGCCUUCAuuacuucaguug
((((((..((((((..(((((((.((.(((((((((((..........))))))))))).)).)))))))..)))))))))))).
((((((..((((((..(((((((.((.(((((((((((..........))))))))))).)).)))))))..)))))))))))).
Structure
- uc uU U C ucca aacugg ggugau AGGUAGU UC UGUUGUUGGGa c |||||| |||||| ||||||| || ||||||||||| uugacu ucauuA UCCGUCA AG ACGACAGCUcu c g -- CU C C cuuu
Annotation confidence
High
Do you think this miRNA is real?
Comments
miR-196b is predicted based on sequence homology to miR-196a [1]. Yekta et al. report that miR-196 miRNAs are expressed from HOX gene clusters in mammals, and that HOX genes in these clusters are targets of miR-196. Indeed, HOXB8 mRNA was shown to be a natural target for miR-196-directed cleavage through a perfectly complementary miR-target site. Other HOX genes have imperfect miR-196 complementary sites indicative of regulation by translational repression [1]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.
Genome context
chr4: 82284851-82284935 [-]
Database links
Mature rno-miR-196b-5p
| Accession | MIMAT0001082 |
| Description | Rattus norvegicus rno-miR-196b-5p mature miRNA |
| Sequence | 16 - UAGGUAGUUUCCUGUUGUUGGG - 37 |
| Evidence |
experimental
cloned [2], SOLiD [3] |
Mature rno-miR-196b-3p
| Accession | MIMAT0017171 |
| Description | Rattus norvegicus rno-miR-196b-3p mature miRNA |
| Sequence | 51 - UCGACAGCACGACACUGCCUUCA - 73 |
| Evidence |
experimental
SOLiD [3] |
References
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