Stem-loop blv-mir-B4

Accession

MI0022564

Description

Bovine leukemia virus blv-mir-B4 precursor miRNA

Sequence

GCGGGAGGCUCUGGUGCUGGggauaagauguggcccuUAGCACCACAGUCUCUGCGCCUUU
((((((((((.(((((((((((............))))))))))).))))))).)))....

Structure

----   -       C           auaag 
    GCG GGAGGCU UGGUGCUGGgg     a
    ||| ||||||| |||||||||||      
    CGC UCUCUGA ACCACGAUucc     u
UUUC   G       C           cggug 

Annotation confidence Not enough data

Genome context

K02120.1: 6702-6762 [+]

Clustered miRNAs

4 other miRNAs are < 10 kb from blv-mir-B4

Mature blv-miR-B4-3p

• Accession: MIMAT0025864
• Description: Bovine leukemia virus blv-miR-B4-3p mature miRNA
• Sequence: 38 - UAGCACCACAGUCUCUGCGCCUUU - 61
• Evidence: experimental ; SOLiD [1], Illumina [2]

Mature blv-miR-B4-5p

• Accession: MIMAT0027347
• Description: Bovine leukemia virus blv-miR-B4-5p mature miRNA
• Sequence: 1 - GCGGGAGGCUCUGGUGCUGG - 20
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 22308400
   RNA virus microRNA that mimics a B-cell oncomiR
   "Kincaid RP, Burke JM, Sullivan CS"
   "Proc Natl Acad Sci U S A (2012) 109:3077-3082


2. PubMed ID: 23345446
   Deep sequencing reveals abundant noncanonical retroviral microRNAs in B-cell leukemia/lymphoma
   "Rosewick N, Momont M, Durkin K, Takeda H, Caiment F, Cleuter Y, Vernin C, Mortreux F, Wattel E, Burny A, Georges M, Van den Broeke A"
   "Proc Natl Acad Sci U S A (2013) 110:2306-2311