Stem-loop aae-mir-13

Accession

MI0013463

Description

Aedes aegypti aae-mir-13 precursor miRNA

Sequence

14788 reads, 755 reads per million, 2 experiments

gucgugaucggaUCGUAAAAAUGGUUGUGCUGUGuuguuacgcucgaaauucaUAUCACAGCCAUUUUGACGAGUUcgauccug
...(.(((((((((((.((((((((((((.((((..(((........))).)))).)))))))))))).)))).))))))))..

Structure

guc u       -    A            C    uu   acg 
   g gaucgga UCGU AAAAUGGUUGUG UGUG  guu   c
   | ||||||| |||| |||||||||||| ||||  |||    
   c cuagcUU AGCA UUUUACCGACAC AUac  uaa   u
-gu -       G    G            U    -u   agc 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

supercont1.268: 888736-888819 [-]

Clustered miRNAs

4 other miRNAs are < 10 kb from aae-mir-13

Mature aae-miR-13-5p

• Accession: MIMAT0014255
• Description: Aedes aegypti aae-miR-13-5p mature miRNA
• Sequence: 13 - UCGUAAAAAUGGUUGUGCUGUG - 34
• Evidence: experimental ; Illumina [2]

Mature aae-miR-13-3p

• Accession: MIMAT0014256
• Description: Aedes aegypti aae-miR-13-3p mature miRNA
• Sequence: 54 - UAUCACAGCCAUUUUGACGAGUU - 76
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119