Stem-loop aae-mir-34

Accession

MI0013456

Description

Aedes aegypti aae-mir-34 precursor miRNA

Literature search

5 open access papers mention aae-mir-34
(26 sentences)

Sequence

922392 reads, 45559 reads per million, 2 experiments

caaggcaauacgcuaUGGCAGUGUGGUUAGCUGGUUGuguagaacuuuggggggcuuccguggcguucgcgcgcacacgggggcucagauucaCAACCACUAUCCGCCCUGCCGCCgcgaggugccagg
...((((...(((..((((((.((((.(((.((((((((............(((((((((((((((....)))).))))))))))).....))))))))))).)))).))))))..)))...))))...

Structure

caa    aua   ua      U    U   C        uagaacuuuggg           -    u 
   ggca   cgc  UGGCAG GUGG UAG UGGUUGug            gggcuuccgug gcgu c
   ||||   |||  |||||| |||| ||| ||||||||            ||||||||||| ||||  
   ccgu   gcg  GCCGUC CGCC AUC ACCAACac            cucgggggcac cgcg g
gga    gga   CC      C    U   -        -------uuaga           a    c 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

supercont1.265: 509521-509649 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from aae-mir-34

Mature aae-miR-34-5p

• Accession: MIMAT0014245
• Description: Aedes aegypti aae-miR-34-5p mature miRNA
• Sequence: 16 - UGGCAGUGUGGUUAGCUGGUUG - 37
• Evidence: experimental ; 454 [1], Illumina [2]

Mature aae-miR-34-3p

• Accession: MIMAT0014246
• Description: Aedes aegypti aae-miR-34-3p mature miRNA
• Sequence: 94 - CAACCACUAUCCGCCCUGCCGCC - 116
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119