Stem-loop aae-mir-11

Accession

MI0013453

Description

Aedes aegypti aae-mir-11 precursor miRNA

Literature search

4 open access papers mention aae-mir-11
(8 sentences)

Sequence

29712 reads, 1495 reads per million, 2 experiments

aacauugaugcgaguagugccgcgcgAGAACUCCGGCUGUGACCUGUGuacacuuuauccaaaucaCAUCACAGUCUGAGUUCUUGCUuggaggcucgucgaucaacuaaugga
....(((((((((((....(((.((((((((((.((((((((..((((................)))))))))))).)))))))))).)))..))))))..)))))........

Structure

----aaca     --      agug   c          C        CC    uacacuu 
        uugau  gcgagu    ccg gcgAGAACUC GGCUGUGA  UGUG       u
        |||||  ||||||    ||| |||||||||| ||||||||  ||||        
        aacua  ugcucg    ggu CGUUCUUGAG CUGACACU  ACac       a
agguaauc     gc      --ga   U          U        --    uaaaccu 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

supercont1.744: 321996-322109 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from aae-mir-11

Mature aae-miR-11-5p

• Accession: MIMAT0014241
• Description: Aedes aegypti aae-miR-11-5p mature miRNA
• Sequence: 27 - AGAACUCCGGCUGUGACCUGUG - 48
• Evidence: experimental ; 454 [1], Illumina [2]

Mature aae-miR-11-3p

• Accession: MIMAT0014242
• Description: Aedes aegypti aae-miR-11-3p mature miRNA
• Sequence: 67 - CAUCACAGUCUGAGUUCUUGCU - 88
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119