Stem-loop aae-mir-278

Accession

MI0013450

Description

Aedes aegypti aae-mir-278 precursor miRNA

Literature search

2 open access papers mention aae-mir-278
(4 sentences)

Sequence

2442 reads, 124 reads per million, 2 experiments

uggugcgaACGGACGAUAGUCUUCAGCGGCCgugcauuugauagaauuggUCGGUGGGACUUUCGUCCGUUUguaaccgcc
.(((((((((((((((.(((((.((.((((((...((((....)))))))))).))))))).)))))))))))).)))...

Structure

--u   -            U     U  G      ugc    g 
   ggu gcgaACGGACGA AGUCU CA CGGCCg   auuu a
   ||| |||||||||||| ||||| || ||||||   ||||  
   cca ugUUUGCCUGCU UCAGG GU GCUggu   uaag u
ccg   a            U     -  G      ---    a 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

supercont1.16: 3596261-3596341 [+]

Mature aae-miR-278-5p

• Accession: MIMAT0014237
• Description: Aedes aegypti aae-miR-278-5p mature miRNA
• Sequence: 9 - ACGGACGAUAGUCUUCAGCGGCC - 31
• Evidence: experimental ; 454 [1], Illumina [2]

Mature aae-miR-278-3p

• Accession: MIMAT0014238
• Description: Aedes aegypti aae-miR-278-3p mature miRNA
• Sequence: 51 - UCGGUGGGACUUUCGUCCGUUU - 72
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119