miRBase entry: aae-mir-306

Stem-loop aae-mir-306


Accession
MI0013446
Description
Aedes aegypti aae-mir-306 precursor miRNA

Literature search
4 open access papers mention aae-mir-306
(28 sentences)

Sequence

2190 reads, 110 reads per million, 2 experiments
cauucgcaauuucaccgguUCAGGUACUGAGUGACUCUCAGaugugcauuucucaagcaaucucguccucaggaccugagguugaaaaacccuGAGAGCACCUCGGUAUCUAAGCcaguguugcgaaaa
..(((((((...(((.((((.((((((((((((.(((((((...(((.........)))...(((.((((((...)))))).)))......))))))))).)))))))))).)))).))))))))))..

Structure
ca       uuu   c    C          -  A       augugcauuucucaagcaauc   u      g 
  uucgcaa   cac gguU AGGUACUGAG UG CUCUCAG                     ucg ccucag  
  |||||||   ||| |||| |||||||||| || |||||||                     ||| |||||| a
  aagcguu   gug cCGA UCUAUGGCUC AC GAGAGuc                     agu ggaguc  
aa       ---   a    A          C  -       ---------------ccaaaa   u      c 


Annotation confidence High
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Comments
This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context
supercont1.785: 213059-213187 [+]
Clustered miRNAs
2 other miRNAs are < 10 kb from aae-mir-306
Name Accession Chromosome Start End Strand Confidence




Database links

Mature aae-miR-306-5p

Accession MIMAT0014229
Description Aedes aegypti aae-miR-306-5p mature miRNA
Sequence 20 - UCAGGUACUGAGUGACUCUCAG - 41
Evidence experimental
454 [1], Illumina [2]

Mature aae-miR-306-3p

Accession MIMAT0014230
Description Aedes aegypti aae-miR-306-3p mature miRNA
Sequence 94 - GAGAGCACCUCGGUAUCUAAGC - 115
Evidence experimental
Illumina [2]

References

  1. PubMed ID: 19961592
    Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
    Li S, Mead EA, Liang S, Tu Z
    BMC Genomics (2009) 10:581

  2. PubMed ID: 20167119
    Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
    Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
    BMC Genomics (2010) 11:119